西北燥证模型动物宏观观测指标与辨证方法

发布时间：2018-06-29 08:50

本文选题：西北燥证 + 动物模型　；参考：《中华中医药杂志》2013年10期

【摘要】：建立证候动物模型是探索西北燥证微观机制及其防治措施的关键。四诊是辨证的基本手段,虽"天然性差别"使对动物和对人的四诊及辨证方法截然不同,但二者却可统一于"宏观观察"。文章主张借助宏观观察手段,依据西北燥证主、兼分证辨证内容,以指标属性(直接性或间接性)分类为基础,筛选适用于造模动物中医西北燥证辨证的宏观观察指标,搭建造模动物宏观观测指标与人体西北燥证主兼分证症状表现间的对应关系,进而建立SD大鼠中医西北燥证指标结构辨证方案;运用指标量化方案,以等级变量描述SD大鼠各辨证指标及其结构,参照大鼠中医西北燥证指标结构辨证方案,应用对比分析法实现SD大鼠西北燥证主兼分证的辨识,并藉此评价西北燥证动物模型。
[Abstract]:Establishing animal model of syndrome is the key to explore the micro mechanism and prevention measures of northwest dryness syndrome. Four diagnoses are the basic means of syndrome differentiation. Although the "natural difference" makes the four diagnosis and differentiation methods for animals and people very different, they can be unified in "macroscopic observation". Based on macroscopic observation means, according to the content of northwest dryness syndrome differentiation and differentiation of syndrome, and based on the classification of index attribute (direct or indirect), the paper selects the macroscopic observation index suitable for the differentiation of northwest dryness syndrome in animal model animal. The corresponding relationship between macroscopical observation index of model animal and symptoms of northwest dryness syndrome of human body, and then establish the structure differentiation scheme of index of northwest dryness syndrome of SD rats in traditional Chinese medicine. The differentiation indexes and their structures of SD rats were described by rank variables. According to the differentiation scheme of the index structure of northwest dryness syndrome in traditional Chinese medicine, the identification of the main and differential syndromes of northwest dryness syndrome of SD rats was realized by means of comparative analysis, and the animal model of northwest dryness syndrome was evaluated by this method.
【作者单位】：新疆医科大学;
【基金】：国家自然科学基金资助项目(No.81060282) 新疆医科大学青年科研创新基金项目(No.xjc201101)~~
【分类号】：R241;R-332

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