新疆维汉血管性痴呆患者认知功能与心理状态的相关性研究

发布时间：2018-01-04 00:18

本文关键词：新疆维汉血管性痴呆患者认知功能与心理状态的相关性研究　出处：《中国全科医学》2016年S1期 　论文类型：期刊论文

【摘要】：目的分析新疆维吾尔族、汉族血管性痴呆(VD)患者认知功能与心理状态的相关性。方法选取2012-2014年在新疆医科大学附属第二医院、附属中医医院收治的130例VD患者,分为维族痴呆组(UVD)50例,汉族痴呆组(HVD)80例;同期收集的体检健康志愿者160例,分为维族正常对照组(Ucon)80例,汉族正常对照组(Hcon)80例。受试者均给予蒙特利尔认知评估量表(MoCA)进行认知功能评估,广泛性焦虑量表(GAD-7)、抑郁自测量表(PHQ-9)结合抑郁自评量表(SDS)及焦虑自评量表(SAS)进行心理状态评估。结果UVD与Ucon,HVD与Hcon的MoCA评分总分以及定向力、记忆力、注意力及计算力、抽象能力、语言、视空间/执行功能、命名评分比较,差异有统计学意义(P0.05)。UVD与HVD的注意力及计算力、视空间/执行功能评分比较,差异有统计学意义(P0.05)。维吾尔族VD患者和汉族VD患者的MoCA评分中的视空间、执行功能和心理状态量表GAD-7及PHQ-9评分呈负相关(P0.05)。结论新疆维、汉两民族VD患者存在焦虑、抑郁障碍,VD患者认知功能与心理健康状态存在一定相关性。
[Abstract]:Objective to analyze the correlation between cognitive function and mental state in patients with vascular dementia (VD) in Xinjiang Uygur and Han nationality. Methods the patients were selected in the second affiliated Hospital of Xinjiang Medical University from 2012-2014. 130 VD patients treated in affiliated TCM Hospital were divided into UVD group (n = 50) and Han nationality group (n = 80). At the same time, 160 healthy volunteers were divided into Uygur normal control group (Uygur) group (n = 80) and control group (n = 80). All the subjects were given the Montreal Cognitive Assessment scale (MoCA) to evaluate their cognitive function and the generalized anxiety scale (GAD-7). Results UVD and Ucon were used to evaluate the mental state of patients with depression self-assessment scale (PHQ-9) and self-rating depression scale (SDS) and anxiety self-rating scale (SAS). The MoCA scores of HVD and Hcon were compared with those of orientation, memory, attention and calculation, abstract ability, language, visual space / executive function, and naming score. The difference was statistically significant (P 0.05). UVD was compared with HVD's attention and computational power, visual space / executive function score. The difference was statistically significant (P 0.05). Visual space in MoCA scores of VD patients in Uygur nationality and VD patients in Han nationality. There was a negative correlation between executive function and mental state scale (GAD-7) and PHQ-9 score (P 0.05). Conclusion there are anxiety and depression disorder in VD patients of Xinjiang and Han nationalities. There was a certain correlation between cognitive function and mental health in VD patients.
【作者单位】：新疆医科大学第二附属医院神经内科;新疆医科大学附属中医医院脑病二科;
【基金】：新疆维吾尔自治区自然科学技术基金面上项目(2014211C088)
【分类号】：R749.13
【正文快照】： 作者单位:830002新疆乌鲁木齐市,新疆医科大学第二附属医院神经内科(李海涛,哈斯也提·依不来音,朱国峰,马依日木·赛买提,阿依吐拉·卡迪尔,王丹,杨新玲);新疆医科大学附属中医医院脑病二科(李桂花)血管性痴呆(vascular dementia,VD)是神经科的常见疾病,其不仅危害患者的身体

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