简化认知行为治疗对广泛性焦虑患者生活质量的影响

发布时间：2018-01-18 16:13

本文关键词：简化认知行为治疗对广泛性焦虑患者生活质量的影响　出处：《上海交通大学学报(医学版)》2015年10期 　论文类型：期刊论文

【摘要】：目的比较简化认知行为治疗(SCBT)、药物治疗以及联合治疗3种干预方式对广泛性焦虑(GAD)患者生活质量的影响。方法针对符合DSM-5中GAD标准,目前处于发作期的患者,运用SCBT方法,采用多中心平行对照、盲法评估的方法,分为SCBT组、SCBT+药物组和药物组。主要结局指标为生命质量评分。结果完成8周干预103例患者,男51例,女52例,平均年龄是(37.8±11.6)岁;3组分别为32、38、33例,3组在年龄、性别和教育程度等方面的差异无统计学意义(P0.05)。基线时3组间仅在社会功能上差异有统计学意义(F=3.469,P=0.035),SCBT+药物组明显低于其他两组;8周末,协方差分析结果表明,3组仅在躯体疼痛上差异有统计学意义(F=3.644,P=0.030),药物组明显高于其他两组。组内比较结果显示:SCBT组除躯体健康问题导致的角色受限、生命活力维度外,其他6个维度量表评分在治疗前后的差异有统计学意义(P0.05);SCBT+药物组在8个维度上治疗前后的差异均有统计学意义(P0.05);药物组除躯体功能,其他7个维度量表评分在治疗前后的差异有统计学意义(P0.05)。3组间HAMA评分差异有统计学意义(P0.05);3组HAMD评分差异无统计学意义(P0.05)。结论单用SCBT、药物治疗及联合治疗3种干预方式均有助于改善GAD患者的生活质量,三者间差异不显著。
[Abstract]:Objective to compare the simplified cognitive behavior therapy (SCBT). Effects of drug therapy and combined therapy on the quality of life of patients with generalized anxiety disorder. The SCBT group was divided into two groups using SCBT method, multicenter parallel control method and blind method. Results after 8 weeks of intervention, there were 51 males and 52 females, with an average age of 37.8 卤11.6 years. The age of the 3 groups were 32and 3833 cases respectively. There was no significant difference in sex and education level (P 0.05). At baseline, there were only significant differences in social function among the three groups (P < 0.05). The SCBT group was significantly lower than the other two groups. At the end of the 8th week, the results of covariance analysis showed that there was only significant difference in somatic pain among the three groups. The drug group was significantly higher than the other two groups. The results of intra-group comparison showed that the body health problems caused by the role limitation and vitality dimension in the SCBT group. The scores of the other six dimensions were significantly different before and after treatment (P 0.05). In SCBT group, there were significant differences in eight dimensions before and after treatment (P 0.05). In the drug group, there were significant differences in the scores of the other seven dimensional scales before and after treatment except for the somatic function. There were significant differences in the HAMA scores between the groups before and after treatment (P 0.05). There was no significant difference in HAMD scores among the three groups (P 0.05). Conclusion the three intervention methods of single SCBT, drug therapy and combined therapy are helpful to improve the quality of life of GAD patients. There was no significant difference among the three groups.
【作者单位】：上海交通大学医学院附属精神卫生中心;
【基金】：科技部“十二五”国家科技支撑项目(2012BAI01B04)~~
【分类号】：R749.72
【正文快照】： 焦虑障碍在普通人群中发病率达到6%以上[1],排除标准:1目前患严重躯体疾病、重度焦虑状部分(15%~48%)常常迁延为慢性病程,严重影响患态或重度惊恐发作者。2有自伤行为或明显自杀倾者的生活质量[2,3]。广泛性焦虑(generalized anxiety向者。3具有精神病性症状,排除强迫症和创伤

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