41例HIV相关的精神病病人的临床特点分析

发布时间：2018-02-15 05:10

本文关键词： 艾滋病病人精神疾病临床特点治疗转归　出处：《中国艾滋病性病》2017年06期 　论文类型：期刊论文

【摘要】：目的分析艾滋病病毒(HIV)相关的精神疾病的患病率、临床特点、治疗及转归,为HIV相关的精神疾病病人的诊疗提供依据。方法对云南省传染病专科医院/艾滋病关爱中心2008年1月至2014年4月首次住院的HIV感染者/艾滋病(AIDS)病人(简称HIV/AIDS病人)及相关精神疾病的病人进行回顾分析。结果 3 921例HIV/AIDS住院病人中,HIV相关的精神疾病41例,患病率为1.05%;平均年龄(38.07±10.23)岁(31~40)岁,无业者19例(46.34%),静脉吸毒传播的21例(51.22%),异性性传播18例(43.90%),合并丙型肝炎17例(41.46%),合并乙型肝炎2例(4.88%)。41例HIV相关的精神病组病人中,20例有抑郁症,10例谵妄,9例痴呆,抑郁及躁狂双向表现者2例;其中21例有明显的自杀倾向,20例有妄想。41例均给予精神科药物治疗及抗病毒治疗(ART)和心理专科治疗。ART半年随访监测CD4~+T淋巴细胞计数平均增长120个/μL,病毒载量检测均低于检测下限。在ART过程中依然给以精神科药物维持治疗,给予心理疏导治疗,41例病人均未出现精神病发作现象。结论 HIV/AIDS病人中精神病患病率高,以青壮年为主,多合并静脉吸毒病史,临床上主要表现为抑郁症,通过抗病毒治疗和抗精神病药物治疗,大多数病人能有效控制病情。
[Abstract]:Objective to analyze the prevalence, clinical characteristics, treatment and outcome of mental disorders associated with HIV / AIDS. Methods to provide the basis for the diagnosis and treatment of patients with mental illness associated with HIV. Methods the patients with HIV / AIDSdisease (HIV/AIDS disease) who were first hospitalized in Yunnan Special Infectious Diseases Hospital / AIDS Care Center from January 2008 to April 2014 were selected as the basis for diagnosis and treatment. Results among the 3 921 inpatients with HIV/AIDS, 41 had HIV-related mental disorders. The average age was 38.07 卤10.23 years old. Among the 19 cases of unemployed, 21 cases of intravenous drug abuse, 18 cases of heterosexual transmission, 17 cases of hepatitis C, 17 cases of hepatitis C, 2 cases of hepatitis B, 4. 88% and 41 cases of HIV related psychosis, 20 cases had depression and 9 cases of delirium dementia. Depression and mania in 2 cases; Of them, 21 cases had obvious suicidal tendency, 20 cases had delusion. 41 cases were treated with psychotherapy and antiviral therapy (ART) and psychological specialty treatment. The half year follow-up monitoring CD4T lymphocyte count increased by 120 cells / 渭 L, virus load test. All the tests were below the detection limit. During the course of ART, the patients were still treated with psychotropic drugs. Conclusion the prevalence rate of psychosis in 41 patients with HIV/AIDS is high, mainly in the young and middle-aged, and most of them have a history of intravenous drug abuse, and the main clinical manifestations are depression. Through antiviral and antipsychotic treatment, most patients can effectively control their condition.
【作者单位】：云南省传染病专科医院/艾滋病关爱中心;
【分类号】：R512.91;R749

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