安徽某市吸毒人群HEV感染的现况调查分析

发布时间：2018-03-23 01:12

本文选题：戊型肝炎　切入点：戊型肝炎病毒　出处：《现代预防医学》2014年15期 　论文类型：期刊论文

【摘要】：目的了解吸毒人群戊型肝炎病毒(HEV)感染情况,分析此人群高危行为方式与HEV感染之间的联系,为预防和控制戊型肝炎提供依据。方法采用横断面研究,从戒毒所和美沙酮门诊选择379名吸毒者,调查其吸毒行为方式、性行为特点,用ELISA法检测HEV-IgG抗体,分析吸毒人群戊型肝炎感染的影响因素。结果调查人群静脉注射吸毒的比例为52.8%,吸毒人群戊肝感染率为8.4%,40岁以上年龄组人群HEV感染率为16.3%,高于其他年龄组感染率(χ2=10.580,P=0.005);吸食海洛因的人群HEV感染率为12.0%,高于吸食冰毒人群的3.4%和吸食其他毒品人群的6.3%,差异有统计学意义(χ2=8.542,P=0.014);静脉吸毒人群的感染率为12.5%,高于非静脉吸毒人群的3.9%,差异有统计学意义(χ2=9.015,P=0.003)。结论静脉注射吸毒和年龄因素可能是吸毒人群HEV高感染的重要因素。
[Abstract]:Objective to investigate the prevalence of hepatitis E virus (HEV) infection in drug users, and to analyze the relationship between high risk behavior patterns and HEV infection in this population, so as to provide a basis for the prevention and control of hepatitis E. methods A cross-sectional study was used. 379 drug users were selected from drug treatment center and methadone clinic to investigate their drug use behavior and sexual behavior characteristics. HEV-IgG antibody was detected by ELISA method. Results the proportion of intravenous drug use was 52.8% and the infection rate of hepatitis E among drug users was 8.40.The infection rate of HEV in the age group over 40 years old was 16.3%, which was higher than that in other age groups. The HEV infection rate of heroin addicts was 12.0, which was higher than that of meth users (3.4%) and other drug users (6.30.14%) (蠂 2 8.542). The infection rate of intravenous drug users was 12.5b, which was higher than that of non-intravenous drug users (3.9%). Conclusion intravenous drug use and age may be important factors for high HEV infection in drug users.
【作者单位】：马鞍山市疾病预防控制中心;皖南医学院;马鞍山市医疗集团临床检验中心;
【基金】：安徽省卫生厅项目(2011Y0104) 皖南医学院重点科研项目培育基金(WK2012Z02)
【分类号】：R512.6;R749.64

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