四二五合方合甘麦大枣汤治疗围绝经期抑郁症临床观察

发布时间：2018-04-01 20:04

本文选题：抑郁症　切入点：围绝经期　出处：《中国中医基础医学杂志》2014年09期

【摘要】：目的:观察四二五合方合甘麦大枣汤治疗围绝经期抑郁症的临床疗效。方法:将40例围绝经期抑郁症患者按随机数字表法分为治疗组和对照组各20例。对照组用雌激素治疗,治疗组在对照组的基础上加用中药四二五合方合甘麦大枣汤治疗,观察2组临床疗效,对比治疗前后改良Kupperman、HAMD抑郁量表评分及FSH、LH、E2水平。结果:治疗组临床疗效总有效率为90%,对照组为75%,治疗组明显优于对照组(P0.05)。治疗组改良Kupperman及HAMD抑郁量表评分减分率显著高于对照组(P0.05),E2水平升高明显高于对照组(P0.05)。结论:四二五合方合甘麦大枣汤治疗围绝经期抑郁症疗效确切。
[Abstract]:Objective: to observe the clinical curative effect of the treatment of peri-menopausal depression with the combination of four twenty-five prescriptions and Ganmai Dazao decoction. Methods: forty patients with postmenopausal depression were randomly divided into two groups: treatment group (n = 20) and control group (n = 20), and control group (n = 20) treated with estrogen. On the basis of the control group, the treatment group was treated with the combination of traditional Chinese medicine four twenty-five formula and Ganmai Dazao decoction, and the clinical efficacy of the two groups was observed. Results: the total effective rate was 90 in the treatment group and 75 in the control group. The score of modified Kupperman and HAMD depression scale in the treatment group was significantly better than that in the control group (P 0.05). The scores of modified Kupperman and HAMD depression scale in the treatment group were significantly lower than those in the control group. The level of E _ 2 was significantly higher than that of control group (P 0.05). Conclusion: it is effective to treat perimenopausal depression with the combination of four Erwu decoction and Ganmai Dazao decoction.
【作者单位】：南阳理工学院张仲景国医学院;南阳理工学院附属医院;
【分类号】：R749.4

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