不同戒断期药物成瘾者注意控制能力的ERP研究

发布时间：2018-04-03 15:02

本文选题：药物成瘾　切入点：戒断期　出处：《中国临床心理学杂志》2017年01期

【摘要】：目的:本研究采用刺激反应协同性任务(Flanker)考察不同戒断时长的药物成瘾者注意控制能力的损伤与恢复情况(短期戒断组:平均戒断2.43个月;长期戒断组:平均戒断47.74个月);方法:实验中要求药物戒断者与正常控制组完成颜色Flanker任务,判断三张同时呈现的图片中中间面孔的颜色与两侧面孔的颜色是否一致。结果:行为结果发现,三组被试对颜色非协同任务的反应时,都显著长于颜色协同任务的反应时,出现了显著的颜色协同效应。脑电结果发现,正常对照组的颜色N200效应在额区的三个电极点Fz、FCz、Cz均显著,长期戒断组与正常对照组相比,颜色N200效应出现在Fz、FCz两个电极点,然而短期戒断组颜色N200效应在三个电极位置均消失。结论:本研究结果说明,长期药物成瘾会造成个体注意控制能力的损伤,表现为短期戒断组颜色N200效应的消失。戒断4年后,长期戒断组注意控制能力基本恢复至正常水平。
[Abstract]:Objective: to investigate the damage and recovery of attention control ability in drug addicts with different abstinence duration by stimulating response synergistic task (Flanker) (short withdrawal group: average 2.43 months withdrawal);Methods: the drug abstinent group and the normal control group were asked to complete the color Flanker task in order to judge whether the color of the middle face in the three simultaneous images was the same as the color of the bilateral face.Results: the behavioral results showed that the response time of the three groups to the color non-cooperative task was significantly longer than that of the color co-task, and there was a significant color synergistic effect.The results of EEG showed that the color N200 effect in the normal control group was significant at the three electrode points of the frontal area, and that in the long-term abstinence group compared with the normal control group, the color N200 effect appeared at the two electrode points of the Fzn FCz.However, in the short-term withdrawal group, the color N 200 effect disappeared at all three electrode locations.Conclusion: the results of this study suggest that long-term drug addiction may lead to the impairment of individual attention and control ability, which is characterized by the disappearance of color N200 effect in short-term withdrawal group.After 4 years of abstinence, the attention control ability of long-term abstinence group basically returned to normal level.
【作者单位】：北京师范大学中国基础教育质量监测协同创新中心;北京师范大学心理学院应用实验心理北京市重点实验室;北京市天堂河戒毒康复所;南京大学社会学院心理学系;认知神经科学与学习国家重点实验室(北京师范大学);北京师范大学情绪调节研究中心;
【基金】：北京市教育委员会共建项目建设计划资助(403101) 国家社科基金重大项目(11&ZD187) 尚善基金的资助 2015年度北京师范大学青年教师基金项目(310422102)资助
【分类号】：R749.61

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