解郁安神汤治疗肝气郁结型躯体症状障碍的临床疗效观察

发布时间：2018-04-10 23:19

本文选题：躯体症状障碍 + 解郁安神汤　；参考：《广西中医药大学》2017年硕士论文

【摘要】：目的:本研究旨在观察解郁安神汤治疗躯体症状障碍的临床疗效。方法:研究以2016年01月至2017年01月在我院门诊就诊或住院的符合诊断标准的60例患者为研究对象,按随机数字表法分为盐酸度洛西汀对照组和解郁安神汤联合盐酸度洛西汀胶囊治疗组各30例,分别对比治疗前、治疗2周、4周、8周后两组的HAMA评分、HAMD评分、SCL-90评分、中医症状积分及不良反应量表(TESS),以评价解郁安神汤治疗躯体症状障碍的有效性。结果:1、治疗后两组的HAMA评分、HAMD评分及中医症状积分均较治疗前下降,差异有统计学意义(P0.05或P0.01)。治疗组的HAMA评分、HAMD评分及中医症状积分在治疗2、4、8周后低于对照组的相应分值,差异有统计学意义(P0.05或P0.01)。2、在SCL-90量表中,治疗后两组的躯体化、焦虑、抑郁、精神病性因子分及总分均较治疗前下降,差异有统计学意义(P0.05)。治疗组在治疗2、4、8周后的躯体化、焦虑、抑郁、精神病性因子分及总分均低于对照组的相应分值,差异有统计学意义(P0.05或P0.01)。3、在改善躯体化症状方面,治疗组的总有效率(89.29%)高于对照组的总有效率(60.87%),差异有统计学意义(P0.05)。4、在整个疗程中,治疗组的副反应总发生率低于对照组的副反应总发生率,差异有统计学意义(P0.05)。结论:解郁安神汤不仅能够改善SSD患者的焦虑、抑郁、精神病性及躯体症状,而且能减少盐酸度洛西汀胶囊所引起的不良反应。
[Abstract]:Objective: to observe the clinical effect of Jieyu Anshen decoction on somatic symptom disorder.Methods: from January 2016 to January 2017, 60 patients who met the diagnostic criteria were studied.According to the method of random digital table, the two groups were divided into two groups: control group (n = 30) and control group (n = 30) treated with Jiayu Anshen decoction combined with duloxetine hydrochloride (n = 30). The HAMA score and the SCL-90 score of the two groups were compared before and after 2 weeks and 4 weeks and 8 weeks after treatment respectively.TCM symptom score and adverse reaction scale were used to evaluate the efficacy of Jieyu Anshen decoction in the treatment of somatic symptom disorder.Results the HAMA scores and TCM symptom scores of the two groups were significantly lower than those before treatment (P 0.05 or P 0.01).The HAMA score and TCM symptom score in the treatment group were significantly lower than those in the control group after 8 weeks of treatment (P 0.05 or P 0.01). In the SCL-90 scale, the somatization, anxiety and depression of the two groups after treatment were significantly lower than those in the control group.The scores of psychotic factors and total scores were lower than those before treatment, and the difference was statistically significant (P 0.05).The scores of somatization, anxiety, depression, psychotic factors and total scores in the treatment group were lower than those in the control group after 8 weeks of treatment (P 0.05 or P 0.01).The total effective rate of treatment group (89.29) was higher than that of control group (60.87%), the difference was statistically significant (P 0.05). During the whole course of treatment, the total incidence of side effects in treatment group was lower than that in control group (P 0.05).Conclusion: Jieyu Anshen decoction can not only improve the anxiety, depression, psychosis and somatic symptoms of SSD patients, but also reduce the adverse reactions caused by Duloxetine Hydrochloride capsule.
【学位授予单位】：广西中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R749

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