抑郁症患者工作记忆容量不足研究

发布时间：2018-04-14 08:17

  本文选题：抑郁症 + 注意引导　； 参考：《中国神经精神疾病杂志》2017年03期

【摘要】：目的通过考察个体在不同工作记忆负载条件产生的注意引导效应,探究抑郁症患者与正常对照工作记忆容量的差异,了解抑郁症患者工作记忆缺损的特点。方法采用视觉工作记忆任务和视觉搜索任务相结合的双任务范式,评估注意引导效应,比较24例首发未用药的轻中度抑郁症患者以及24例正常对照在无效条件和控制条件下的反应时。结果低记忆负载时两组无效条件和控制条件反应时差异均有统计学意义(P0.01),两组都有注意引导效应;高记忆负载时,抑郁组无效条件和控制条件反应时差异无统计学意义(P0.05),注意引导效应消失。在高记忆负载时,抑郁组无效条件记忆正确率与控制条件记忆正确率的差异有统计学意义(P0.01)。结论与正常对照相比,抑郁症患者的工作记忆容量较小,工作记忆执行功能受损可能体现在注意转换困难上。
[Abstract]:Objective to investigate the individual guidance effect of load conditions in different working memory attention, explore differences depression patients and normal control of working memory capacity, understand the characteristics of working memory impairment in patients with depression. Methods using the dual task paradigm of visual working memory task and a visual search task of combining the evaluation guide effect, 24 cases of first-episode medication in patients with mild to moderate depression patients and 24 normal controls in the invalid condition and control the reaction time under the low memory load. The results of two groups of invalid conditions and control conditions of reaction, the difference was statistically significant (P0.01), the two groups have guide effect; high memory load, there was no significant difference in depression group is invalid conditions and control conditions of reaction time (P0.05), pay attention to guiding effect disappeared. In the high memory load, depression group invalid condition accuracy and memory control The difference between the accuracy rate of the conditional memory was statistically significant (P0.01). Conclusion compared with the normal control, the working memory capacity of the depressed patients is relatively small, and the executive function impairment of working memory may be reflected in the difficulty of attention transformation.

【作者单位】： 新疆师范大学心智发展与学习科学重点实验室;乌鲁木齐第四人民医院;广州大学;
【分类号】：R749.4
，

本文编号：1748437