住院精神病患者传染性病原体感染及免疫功能研究

发布时间：2018-04-14 15:04

  本文选题：精神病 + 住院　； 参考：《中华医院感染学杂志》2017年11期

【摘要】：目的探讨住院精神病患者传染性病原体感染及免疫功能状况,为精神病患者传染性病原体感染的预防治疗提供参考。方法选取2012年1月-2016年1月在医院住院治疗1 400例精神病患者,入院后行乙型肝炎病毒(HBV)、丙型肝炎病毒(HCV)、人类免疫缺陷病毒(HIV)、梅毒螺旋体(TP)抗原或抗体及免疫功能相关指标(IgA、IgG、IgM、C3、C4)检测。结果 1 400例精神病患者中68例感染传染病病原体,感染率为4.86%,其中单一病原体感染39例、混合感染29例,分别占57.35%、42.65%,单一感染中以HBV感染所占比例最高占35.29%,混合感染中以HBV+TP感染所占比例最高占23.53%;HBV、HCV、HIV、TP感染者分别有49例、18例、5例、26例,感染率分别为3.50%、1.29%、0.36%、1.86%;传染性病原体感染患者IgA、IgG、IgM、C3及C4水平低于无感染患者,比较差异有统计学意义(P0.05)。结论住院精神病患者传染性病原体感染以HBV及HCV感染为主,混合感染者以HBV+TP两种病原体感染多见,传染性病原体感染患者免疫功能相对较差。
[Abstract]:Objective to investigate infectious pathogen infection and immune function in psychiatric patients in order to provide reference for prevention and treatment of infectious pathogen infection in psychiatric patients.Methods from January 2012 to January 2016, 1 400 psychiatric patients were hospitalized.After admission, hepatitis B virus (HBV), hepatitis C virus (HCV), human immunodeficiency virus (HIV), Treponema pallidum (TPTP) antigen or antibody and immunological function were detected.Results among the 1 400 patients with mental illness, 68 cases were infected with infectious diseases, the infection rate was 4.86%, including 39 cases of single pathogen infection and 29 cases of mixed infection.The proportion of HBV infection was 35.29% in single infection, and the highest in HBV TP infection in mixed infection. There were 49 cases (18 cases) and 5 cases (26 cases) of HBV TP infection in mixed infection, respectively.The infection rates were 3.50 / 1.29 and 0.36 / 1.86, respectively, and the levels of IgAG _ 3 and C _ 4 in patients with infectious pathogens were significantly lower than those in non-infected patients (P 0.05).Conclusion HBV and HCV are the main infectious pathogens in inpatients with psychosis, HBV TP is the most common pathogen in mixed infections, and the immune function of patients with infectious pathogens is relatively poor.
【作者单位】： 河南省洛阳荣康医院老年精神科;洛阳市第一中医院检验科;河南省洛阳荣康医院普通精神科;河南省洛阳荣康医院情感障碍科;洛阳市精神卫生中心普通精神科;
【分类号】：R749
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本文编号：1749816