阿尔茨海默病患者血清基质金属蛋白酶2和9水平的测定

发布时间：2018-04-28 14:58

本文选题：阿尔茨海默病 + 基质金属蛋白酶　；参考：《郑州大学学报(医学版)》2014年01期

【摘要】：正阿尔茨海默病(Alzheimer's disease,AD)是老年期常见的中枢神经系统疾病,是痴呆的主要类型。国外最新的AD诊断标准的推荐指南中已纳入了如脑脊液中β-淀粉样蛋白(Aβ)、Tau蛋白等生物标志物[1],说明生物标志物在AD诊断中的作用日益受到重视,然而具有较高敏感度及特异度的血浆诊断标志物目前尚未找到[2]。基质金属蛋白酶(matrix
[Abstract]:Alzheimer's disease (AD) is a common central nervous system disease in the elderly and is the main type of dementia. Biomarkers such as 尾 -amyloid A 尾 -butenau protein in cerebrospinal fluid (CSF) have been included in the recommended guidelines for the latest diagnostic criteria for AD in foreign countries, indicating that the role of biomarkers in the diagnosis of AD has been paid more and more attention. However, plasma diagnostic markers with high sensitivity and specificity have not been found [2]. Matrix metalloproteinase matrix
【作者单位】：郑州大学第一附属医院神经内科;
【分类号】：R749.16

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