精神分裂症住院天数的影响因素及其临床预测指标

发布时间：2018-04-29 05:38

本文选题：精神分裂症 + 住院天数　；参考：《中国神经精神疾病杂志》2014年06期

【摘要】：目的分析精神分裂症患者临床特征对住院天数的影响,探讨患者住院天数的预测指标,为临床诊疗及预后提供参考依据。方法在广州市脑科医院精神科纳入236例精神分裂症患者,入院1周内及出院前1周采用阳性与阴性症状量表(positive and negative symptom scale,PANSS)、自知力和治疗态度问卷(insight andtreatment attitudes questionnaire,ITAQ)及药物态度清单(drug attitude inventory,DAI)分别评估患者精神症状、自知力及服药态度。分析住院天数与社会人口学资料、入院时的PANSS分、ITAQ分、DAI分,以及各量表出入院分数差值的残差之间关系。结果患者病程(r=0.199,P=0.002)和入院时PANSS阴性症状分(r=0.180,P=0.006)分别与住院天数呈正相关。线性回归分析显示病程(β=0.010,P=0.030)及入院时PANSS阴性症状分(β=0.286,P=0.010)与住院天数相关联。结论病程、入院时PANSS阴性症状水平是精神分裂症患者住院天数长短的临床预测指标,尽早采取积极的综合治疗方法以改善患者阴性症状对缩短住院天数有重要意义。
[Abstract]:Objective to analyze the influence of clinical characteristics of schizophrenia on the days of hospitalization, and to explore the predictors of the days of hospitalization in order to provide reference for clinical diagnosis and treatment and prognosis. Methods 236 schizophrenic patients were enrolled in the Department of Psychiatry, Guangzhou brain Hospital. Within 1 week of admission and 1 week before discharge, positive and negative symptom scale was used to evaluate the mental symptoms, insight and attitude questionnaire of insight andtreatment attitudes questionnaire, and drug attitude list (drug attitude inventory DAI) to evaluate the mental symptoms, insight and medication attitude of the patients. The results were as follows: (1) in the first week of admission and 1 week before discharge from hospital, the positive and negative symptom scale was used to evaluate the mental symptoms, insight and medication attitude of the patients, respectively. The relationship between the length of stay in hospital and the social demography data, the PANSS score and the Dai score at admission, and the residual difference between the scores of each scale were analyzed. Results there was a positive correlation between the duration of PANSS and the duration of the disease (0.199P0. 002) and the negative symptoms of PANSS (0. 180 P0. 006). Linear regression analysis showed that the course of disease (尾 -0.010) and the score of PANSS negative symptoms at admission (尾 -0.286) were correlated with the length of stay. Conclusion the course of disease and the level of PANSS negative symptoms at admission are clinical predictors of the length of stay in schizophrenia. It is important to take active comprehensive treatment to improve the negative symptoms in order to shorten the days of hospitalization.
【作者单位】：广州市脑科医院;
【基金】：国家精神科临床重点专科建设项目子项目基金(编号:201201-001) 广州市医药卫生科技基金(编号:20131A011083)
【分类号】：R749.3

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