阿尔茨海默病患者血糖、血脂水平及冠心病发病的平行对比分析

发布时间：2018-05-02 21:21

本文选题：阿尔茨海默病 + 血糖　；参考：《中国老年学杂志》2017年11期

【摘要】：目的分析阿尔茨海默病患者的血糖、血脂水平以及冠心病发生率与正常老年人的差异性。方法 46例阿尔茨海默病(AD)老年患者作为AD组,以同期行常规体检或接受治疗的46例非AD老年患者作为对照组,对比两组纳入病例资料的血糖水平、血脂水平、炎性因子及冠心病及相关疾病的发生率。结果 AD组患者空腹血糖水平、糖化血红蛋白水平及胰岛素抵抗指数均显著高于对照组(P0.01);AD组空腹胰岛素水平明显高于对照组(P0.05)。AD组TC、TG、HDL-C均显著高于对照组,LDL-C显著低于对照组(均P0.05)。AD组CRP、IL-6水平均显著高于对照组(均P0.01)。AD组患者中冠心病、高血压及高血脂的发生率显著高于对照组(P0.01);AD组与对照组患者中糖尿病发生率无明显差异(P0.05)。结论 AD患者中冠心病的发生率高于普通老年人,冠心病与AD患者均具有血糖、血脂水平偏高的特征,应引起足够重视。
[Abstract]:Objective to analyze the differences of blood glucose, blood lipids and the incidence of coronary heart disease between Alzheimer's disease patients and normal elderly people. Methods 46 elderly patients with Alzheimer's disease were selected as AD group and 46 non-AD patients as control group. The blood glucose and blood lipid levels were compared between the two groups. The incidence of inflammatory factors and coronary heart disease and related diseases. Results the fasting blood glucose level in AD group, The level of glycosylated hemoglobin and insulin resistance index in AD group were significantly higher than those in control group P0.05. AD group were significantly higher than that in control group P0.05. AD group was significantly higher than that in control group, LDL-C level was significantly lower than that in control group (all P0.05).AD group was significantly higher than that in control group). In the control group (all P0.01).AD patients), coronary heart disease, The incidence of hypertension and hyperlipidemia in AD group was significantly higher than that in control group (P 0.01). There was no significant difference in the incidence of diabetes between AD group and control group (P 0.05). Conclusion the incidence of coronary heart disease in patients with AD is higher than that in the elderly. Both CAD and AD patients have the characteristics of high blood glucose and blood lipids, which should be paid more attention to.
【作者单位】：长沙医学院附属第一医院;
【基金】：湖南省科技计划项目(2015JC3059)
【分类号】：R541.4;R749.16

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