双相障碍Ⅰ型患者微小躯体异常的研究

发布时间：2018-05-06 08:51

本文选题：双相障碍 + 微小躯体异常　；参考：《中国神经精神疾病杂志》2014年11期

【摘要】：目的调查双相障碍Ⅰ型患者微小躯体异常(minor physical anomalies,MPAs),了解双相障碍患者是否存在神经发育异常。方法收集16~45岁双相障碍I型患者118例,健康人群101名作为对照组,采用躯体异常量表的部分条目及新增条目进行MPAs评定。结果患者组头顶漩涡对称者较对照组多(52.1%vs.31.4%)而偏右者少(30.9%vs.50.0%);内眦赘皮者较对照组增多(23.7%vs.11.9%);外眼距较对照组增宽[(10.13±0.59)mm vs.(9.88±0.57)mm],差异均有统计学意义(均P0.05)。两组间头围、内眼距、耳际过低、耳末粘附、外耳廓曲线不规则、舌裂纹、通关掌、长的大拇指、右手第二指长度与右手第四手指长度之比(2D:4D)的差异均无统计学意义(P0.05)。结论双相障碍Ⅰ型患者可能存在神经发育异常。
[Abstract]:Objective to investigate minor physical anomalies in patients with bipolar disorder type I and to find out whether there are neurodevelopmental abnormalities in patients with bipolar disorder. Methods one hundred and eighty-eight patients with bipolar disorder type I aged 1645 and 101 healthy people as control group were assessed by MPAs with some items of somatic abnormality scale and new items. Results compared with the control group, there were 52.1 vs.31.4in the patients with symmetrical swirl on the top of the head, 30.9vs.50.0in the right side, 23.7vs.11.9 in the epicanthus and 10.13 卤0.59)mm vs.(9.88 卤0.57)mm in the outer eye distance compared with the control group (all P 0.05). There was no significant difference between the two groups in the head circumference, the distance between the inner eye and the eye, the lower ear, the adhesion of the ear, the irregular curve of the external auricle, the tongue crack, the open palm, the long thumb and the ratio of the length of the second finger of the right hand to the length of the fourth finger of the right hand (2D: 4D). There was no significant difference between the two groups in the length of the second finger and the fourth finger of the right hand. Conclusion there may be neurodevelopmental abnormalities in patients with bipolar disorder type I.
【作者单位】：广州市惠爱医院(广州市精神病医院广州市脑科医院);
【基金】：广东省科技计划项目(编号:) 广州市医药卫生科技项目(编号:20131A011089)
【分类号】：R749.4

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