老年女性性激素水平与遗忘型轻度认知功能障碍的关系

发布时间：2018-05-16 22:29

本文选题：轻度认知功能障碍 + 雌二醇　；参考：《中国妇幼保健》2014年33期

【摘要】：目的:探讨老年女性性激素水平与遗忘型轻度认知功能障碍(a MCI)之间的关系。方法:选择60周岁以上的女性a MCI患者36例为a MCI组,同时选择认知功能正常的女性36例为对照组。采用1∶1配对研究的方法,用放射免疫方法测定两组病例血清性激素的水平并进行对比分析。结果:两组病例间的血清促卵泡生成素、促黄体生成素、孕酮、泌乳素和睾酮水平的差异无统计学意义(P0.05);a MCI组病例的血清雌二醇水平为(15.36±4.21)μg/L,对照组雌二醇水平为(22.31±6.54)μg/L,a MCI组雌二醇水平明显低于对照组(P0.05)。结论:雌二醇水平降低可能是老年女性患a MCI的危险因素之一。
[Abstract]:Objective: to investigate the relationship between sex hormone level and amnesia mild cognitive impairment (MCI) in elderly women. Methods: 36 women over 60 years old with a MCI were selected as a MCI group and 36 women with normal cognitive function as control group. The serum levels of sex hormones in the two groups were measured by radioimmunoassay and compared with each other by 1:1 paired study. Results: serum follicle stimulating hormone, luteinizing hormone, progesterone were found in the two groups. The serum estradiol level in MCI group was 15.36 卤4.21 渭 g / L, and the estradiol level in control group was 22.31 卤6.54 渭 g 路L ~ (-1) 渭 g 路L ~ (-1) 路L ~ (-1). The level of estradiol in MCI group was significantly lower than that in control group (P 0.05). Conclusion: the decrease of estradiol level may be one of the risk factors of a MCI in elderly women.
【作者单位】：浙江省湖州市中心医院神经内科;
【分类号】：R749.16

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