核心症状对孤独症谱系障碍儿童健康相关生命质量的影响

发布时间：2018-05-17 18:46

本文选题：孤独症谱系障碍 + 核心症状　；参考：《中国儿童保健杂志》2016年03期

【摘要】：目的了解孤独症谱系障碍(ASD)的核心症状对患儿健康相关生命质量(HRQoL)的影响。方法以2014年4-10月在重医附属儿童医院儿保科参加结构化训练的患儿为研究对象,采用自设孤独症核心症状问卷及PedsQLTM4.0生命质量家长报告,分析ASD核心症状与PedsQoL总体及各维度的关系。结果 1)核心症状中重复刻板行为及狭隘兴趣与PedsQoL总分、情感及社交功能呈负相关(r=-0.503,-0.600,-0.474,P均0.01),与生理及学校功能无显著相关;社交沟通及社会互动障碍与ASD患儿PedsQoL总分及各功能区均无显著相关。2)轻度重复刻板行为及狭隘兴趣的ASD患儿在PedsQL总得分及各功能区得分均高于重度的患儿,其中在情感及社交功能方面的差异有统计学意义(P0.05),总体生命质量、生理功能、学校功能差异无统计学意义。结论 ASD患儿HRQoL与重复刻板行为及狭隘兴趣有关,重复刻板行为及狭隘兴趣症状越重,ASD患儿的HRQoL越差。改善孤独症患儿重复刻板行为及狭隘兴趣,将有助于提高孤独症患儿HRQoL。
[Abstract]:Objective to investigate the effect of ASD on health related quality of life (HRQoL) in children with autism. Methods Children who took part in structured training in the Department of Child Care of affiliated Children's Hospital from April to October 2014 were selected as the study subjects. The self-designed autism core symptoms questionnaire and PedsQLTM4.0 quality of life parent report were used. To analyze the relationship between the core symptoms of ASD and the overall and various dimensions of PedsQoL. Results 1) there was a negative correlation between stereotypical behavior and narrow interest in the core symptoms and the total score of PedsQoL, emotion and social function (P < 0.01), but no significant correlation with physiological and school functions. There was no significant correlation between the total score of PedsQoL and each functional area in children with ASD. 2) the total score of PedsQL and the score of each functional area in children with mild repeated stereotype behavior and narrow interest were higher than those in children with severe ASD. The differences in emotion and social function were statistically significant (P 0.05), and there was no significant difference in total quality of life, physiological function and school function. Conclusion HRQoL is related to repeated stereotype behavior and narrow interest in children with ASD. The worse the symptoms of repeated stereotype and narrow interest are, the worse HRQoL is in children with ASD. Improving repetitive stereotyping and narrow interests in autistic children will help to improve HROL in autistic children.
【作者单位】：重庆医科大学附属儿童医院;
【分类号】：R749.94

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