伴和不伴污染洗涤症状的强迫性障碍患者的厌恶感

发布时间：2018-06-06 01:19

本文选题：强迫性障碍 + 污染/洗涤　；参考：《中国心理卫生杂志》2017年09期

【摘要】：目的:本研究旨在探讨伴和不伴污染/洗涤症状的强迫性障碍患者之间厌恶感的差异,为强迫性障碍的异质性和个体化治疗提供理论依据。方法:选取符合疾病和有关健康问题的国际统计分类第十次修订本(ICD-10)中强迫性障碍诊断标准的患者66例,根据是否伴有污染/洗涤症状分为清洗组(n=26)及非清洗组(n=40),并选取年龄、性别、受教育程度匹配的正常对照51例。所有被试完成词汇判断任务,记录被试在核心厌恶词、道德厌恶词和中性词厌恶判断中的正确率、反应时及厌恶程度评级结果,比较三组被试厌恶感的差异。结果:清洗组、非清洗组核心厌恶词[(723±89)ms,(746±95)ms vs.(676±96)ms]及道德厌恶词[(772±98)ms,(796±92)ms vs.(723±94)ms]的反应时均高于正常对照组(均P0.01),且前两组核心厌恶词[(6.7±1.5),(6.9±1.6)vs.(5.8±1.7)]及道德厌恶词[(6.8±1.7),(7.2±1.3)vs.(6.3±1.5)]的厌恶程度评级均高于正常对照组(均P0.05)。清洗组与非清洗组在两类厌恶词的正确率、反应时及厌恶程度评级上差异均无统计学意义(均P0.05)。结论:强迫性障碍患者厌恶感均升高,伴和不伴污染/洗涤症状的患者之间厌恶感无差异。厌恶感升高可能与强迫性障碍的发生及发展均有关,降低厌恶感可能是未来强迫性障碍的一个治疗方向。
[Abstract]:Objective: to explore the difference of aversion between patients with and without pollution / washing symptoms and to provide theoretical basis for heterogeneity and individualized treatment of obsessive-compulsive disorder. Methods: a total of 66 patients with obsessive-compulsive disorder (OCD) in ICD-10 (International Statistical Classification of Diseases and related Health problems) were selected and divided into cleaning group (n = 26) and non-cleaning group (n = 40) according to whether they were accompanied with pollution / washing symptoms. Gender, education level matched normal control 51 cases. All subjects completed the task of lexical judgment, and recorded the correct rate, reaction time and aversion rating results of core disgust word, moral loathing word and neutral aversion word, and compared the difference of aversion feeling among the three groups. Results: the reaction time of core disgust words [723 卤89 95)ms vs.(676 卤96)ms] and moral disgust words (772 卤98ms + 796 卤92)ms vs.(723 卤94)ms) in the cleaning group and non-cleaning group were higher than those in the normal control group (all P 0.01), and the scores of the core disgust words [6.7 卤1.56.9 卤1.6)vs.(5.8 卤1.7] and the moral disgust words (6.8 卤1.7 卤1.3)vs.(6.3 卤1.5) in the former two groups were higher than those in the normal control group (all P 0.05). There was no significant difference between the cleaning group and the non-cleaning group in the correct rate, reaction time and aversion degree of the two kinds of disgust words (all P 0.05). Conclusion: the aversion of obsessive-compulsive disorder patients is increased, and there is no difference between the patients with and without pollution / washing symptoms. The increase of aversion may be related to the occurrence and development of obsessive-compulsive disorder, and reducing aversion may be one of the therapeutic directions of obsessive-compulsive disorder in the future.
【作者单位】：安徽医科大学医学心理学系;安徽医科大学精神卫生临床学院安徽省精神卫生中心;
【基金】：上海市“科技创新行动计划”长三角科技联合公关项目子项目(15495810203)
【分类号】：R749.7

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