加味桃红四物汤联合高压氧治疗血管性痴呆临床研究

发布时间：2018-06-12 03:19

  本文选题：血管性痴呆 + 桃红四物汤　； 参考：《中华中医药杂志》2016年08期

【摘要】：目的:观察加味桃红四物汤联合高压氧治疗血管性痴呆(VD)的临床疗效。方法:将160例VD患者随机分为治疗组与对照组,各80例;对照组常规给予抗血小板聚集、降脂稳定斑块、脑保护剂等治疗并进行高压氧舱治疗;治疗组在对照组基础上加用加味桃红四物汤治疗。两组均治疗28d后对患者治疗前后的中医症候、行为能力、精神状态进行疗效评价。结果:经过28d治疗,对治疗前后血管性痴呆辨证量表(SDSVD)、Blessed行为能力量表(BBS)评分比较,治疗组与对照组之间差异显著(P0.01),治疗前后简易精神状态检查(MMSE)量表评分比较积分上升值虽无明显差异,但治疗组的总体有效率高于对照组。结论:加味桃红四物汤治疗VD可以有效的改善患者认知功能受损程度,提高生活质量。
[Abstract]:Objective: to observe the clinical effect of Jiawei Taohong Siwu decoction combined with hyperbaric oxygen on vascular dementia. Methods: 160 patients with VD were randomly divided into treatment group (n = 80) and control group (n = 80). The treatment group was treated with modified Taohong Siwu decoction on the basis of control group. After 28 days of treatment, the two groups were evaluated for the symptoms, behavior and mental state of the patients before and after treatment. Results: after 28 days of treatment, the scores of SDSVD / Blessed Behavioral ability scale (BBS) were compared before and after treatment. The difference between the treatment group and the control group was significant (P 0.01). Although there was no significant difference in the scores of MMSE before and after treatment, the overall effective rate of the treatment group was higher than that of the control group. Conclusion: modified Taohong Siwu decoction can effectively improve the degree of cognitive impairment and improve the quality of life in patients with VD.
【作者单位】： 河北大学附属医院;
【基金】：河北省重大医学科研课题资助项目(No.2013067759)~~
【分类号】：R749.13
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本文编号：2008060