上海地区老年痴呆患者睡眠障碍特点

发布时间：2018-06-17 10:07

本文选题：老年痴呆 + 睡眠障碍　；参考：《中国老年学杂志》2017年03期

【摘要】：目的探讨上海地区老年痴呆(AD)患者睡眠障碍的临床特征,并分析AD患者合并睡眠呼吸暂停综合征(SAS)的睡眠结构特点。方法 AD患者50例为AD组及同期健康体检的老年人50例作为对照组,两组分别进行匹兹堡睡眠质量指数(PQSI)量表、爱泼沃斯思睡量表(ESS)、睡眠日志、多导睡眠检测等项目。结果 AD组与对照组PQSI量表及ESS评分均有统计学差异(P0.05),两组睡眠障碍指标:入眠困难、尖叫、片段睡眠、夜间躁动、不宁腿综合征(RLS)、阻塞性SAS(OSAS)有统计学差异(P0.05),而睡眠障碍指标梦靥两组间无统计学差异(P0.05)。AD组合并SAS与未合并SAS组相比,睡眠总时间(SPT)减少,S1占SPT百分比减少;对照组中合并SAS与未合并SAS组相比,S1及SPT百分比减少而S2则增加(P0.05)。结论 SAS可能加重AD患者和正常老年人睡眠结构障碍,而AD患者加重更明显。
[Abstract]:Objective to investigate the clinical features of sleep disorders in patients with Alzheimer's disease (AD) in Shanghai and to analyze the sleep structure of AD patients with sleep apnea syndrome (SAS). Methods 50 elderly patients with AD and 50 healthy controls were divided into two groups: Pittsburgh Sleep quality Index (PQSI), Epworth sleep scale (ESS), sleep log, polysomnography and so on. Results there were significant differences in PQSI scale and ESS score between AD group and control group (P 0.05). The indexes of sleep disorder in AD group were difficult to sleep, screaming, segment sleep and restlessness at night. There was significant difference in restless leg syndrome (RLSU, obstructive SASS-OSAS) between the two groups (P 0.05), but there was no significant difference in sleep disorder index between the two groups (P 0.05). Compared with the group without SAS, total sleep time (SPT) decreased and the percentage of S 1 to S 1 decreased. The percentage of S _ 1 and SPT in the control group with SAS was lower than that in the control group, while the percentage of S _ 2 was higher than that in the control group (P 0.05). Conclusion SAS may aggravate sleep structure disorder in AD patients and normal elderly people, especially in AD patients.
【作者单位】：上海中医药大学附属曙光医院老年科;荷泽市第三人民医院;
【分类号】：R563.9

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