急性脑梗死患者认知障碍与梗死部位的相关研究

发布时间：2018-06-28 20:54

本文选题：脑梗死 + 认知障碍　；参考：《中风与神经疾病杂志》2017年01期

【摘要】：目的分析急性脑梗死患者不同病灶部位认知障碍的特点。方法采用中文版蒙特利尔认知评估量表(MoCA)对97例单发病灶急性脑梗死患者和20例无脑卒中对照者进行认知功能评估,探讨MoCA 7个分项目(视空间与执行功能EF、命名NAM、注意力ATT、语言功能包括复述与流畅性LANG、抽象概括能力ABS、记忆能力包括瞬时记忆及近记忆MEM、定向力ORT)的评估结果与患者头部MRI影像结果中所示梗死部位之间的关系。结果 (1)97例急性脑梗死患者中MoCA26分者共73例,血管性认知障碍(VCI)总的发生率约为75.26%。(2)额叶部位梗死患者EF与ATT损害明显;颞叶部位梗死患者MEM、EF与ORT损害明显;丘脑部位梗死可能与ATT、LANG、EF损害有关;顶叶部位梗死可能与ORT、EF损害有关;枕叶、基底节部位梗死可能与EF损害有关。小脑、脑桥部位梗死在MoCA总分及分测验中均未显示有统计学意义的变化(P0.05)。结论脑梗死后认知障碍的发生率高;急性脑梗死患者不同梗死部位认知功能损害特点不同。
[Abstract]:Objective to analyze the characteristics of cognitive impairment in patients with acute cerebral infarction. Methods the Chinese version of Montreal Cognitive Assessment scale (MoCA) was used to evaluate the cognitive function of 97 patients with single focal acute cerebral infarction and 20 controls without stroke. The evaluation results of seven sub-projects of MoCA (visual space and executive function EF, named NAM, attention ATT, language function including repetition and fluency long, abstract generalization ability ABS, memory ability including instantaneous memory and near memory MEM, directional force ORT) were discussed. The relationship between the infarct site as shown in the MRI findings of the head of the patient. Results (1) among 97 patients with acute cerebral infarction, there were 73 patients with MoCA26 scores, and the total incidence of vascular cognitive impairment (VCI) was about 75.26.The (2) EF and ATT damage were significant in patients with frontal lobe infarction, the patients with temporal lobe infarction had significant MEMEF and ORT damage. The infarct of thalamus may be related to the damage of ATTN LANGEF, the infarct of parietal lobe may be related to the damage of ORTN EF, and the infarction of occipital lobe and basal ganglia may be related to EF damage. No significant changes were found in the total score and subtest of MoCA in cerebellar and pons infarction (P0.05). Conclusion the incidence of cognitive impairment after cerebral infarction is high, and the characteristics of cognitive impairment are different in patients with acute cerebral infarction.
【作者单位】：锦州医科大学火箭军总医院研究生培养基地;中国人民解放军火箭军总医院神经内科;
【基金】：全军十二五保健专项科研课题(12BJZ24) 军队医学科技青年培育项目(15QNP044)
【分类号】：R749.13

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