GPCOG中文译本在社区中老年人认知筛查中的应用研究

发布时间：2018-07-12 11:03

本文选题：认知损害 + 老年性痴呆　；参考：《华中科技大学》2012年硕士论文

【摘要】：目的：探讨全科医生认知评估量表GPCOG的中文译本在中国社区认知筛查中的应用价值，为基层临床医生及社区全科医生寻找一个简短高效、便于操作、依从性好的认知障碍筛查工具。方法：所有的调查对象采用中文版GPCOG和MMSE进行认知功能调查，其中部分受试者于一周后复查GPCOG检测重测信度。采用精神疾病诊断与统计手册DSM-IV标准[1-2]建立可能老年性痴呆诊断，通过信度、效度和ROC曲线、AUC、约登指数等指标评价GPCOG中文译本在社区老年人认知筛查中的应用价值。结果：共计297人符合入组标准并完成本次调查，平均年龄71.43±9.80岁，检出老年性痴呆患者43人，总检出率14.48%。本研究显示年龄、教育程度与老年性痴呆发病率显著相关（P＜0.01），性别间则无显著差异。本GPCOG中文版Cronbach'sα为0.775，各项目间及与总分间相关系数在0.472~0.929（P＜0.05）之间，仅时间定向与其他各项、总分相关性稍低（0.298~0.503），，GPCOG患者检测部分重测信度0.9498（P=0.000），以上数据均显示出GPCOG具有良好的稳定性和一致性。GPCOG筛查老年性痴呆的灵敏性为93.02%，特异性为84.65%，与MMSE总分经SPearman相关性检验呈显著相关（r=0.761，P=0.000），患者测试部分ROC曲线下面积（AUC）为0.926（标准误=0.017，P=0.000），总分ROC曲线下面积（AUC）为0.933（标准误=0.016，P=0.000），以上数据表明GPCOG效度较好。结论：GPCOG具有较好的信度和效度，敏感性高，是一种适用于基层全科医生的简短高效、便于操作、依从性好的认知障碍筛查工具。
[Abstract]:Objective: To explore the application value of the Chinese version of the general practitioner cognitive assessment scale (GPCOG) in Chinese community cognitive screening, and to find a short, efficient, convenient and compliant cognitive barrier screening tool for clinicians and community general practitioners at the grass-roots level.
Methods: all subjects were investigated using the Chinese version of GPCOG and MMSE to investigate the cognitive function. Some of the subjects reviewed the GPCOG test reliability one week later. The diagnosis of Alzheimer's disease was established by the DSM-IV standard [1-2] of mental disease diagnosis and statistics, and the reliability, validity and ROC curve, AUC, and the Jordan index index were used to evaluate G. The application value of PCOG Chinese version in the cognitive screening of the elderly in the community.
Results: a total of 297 people were in accordance with the standard of entry group and completed the survey. The average age was 71.43 + 9.80 years old. 43 people with Alzheimer's disease were detected. The total detection rate was 14.48%.. This study showed that the education level was significantly related to the incidence of Alzheimer's disease (P < 0.01), and there was no significant difference between the sexes. The Chinese version of the Chinese version of GPCOG was 0.775. The correlation coefficient between the total and the total scores was between 0.472~0.929 (P < 0.05), only time orientation and other items, the correlation of total score was slightly lower (0.298~0.503), and the reliability of GPCOG patients was 0.9498 (P=0.000). The above data showed that GPCOG had good stability and consistency, and the sensitivity of.GPCOG screening for Alzheimer's disease was 93.02%, and the specificity was 93.02%. The sex was 84.65%, and the total score of MMSE was significantly correlated with the SPearman correlation test (r=0.761, P=0.000). The area under the ROC curve (AUC) was 0.926 (standard false =0.017, P=0.000), and the area under the total ROC curve (AUC) was 0.933 (standard error =0.016, P=0.000). Validity and high sensitivity are suitable for general practitioners at the basic level.
Students are short, efficient, easy to operate, and have good compliance with cognitive impairment screening tools.
【学位授予单位】：华中科技大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R749.2

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