精神分裂症患者急性发作和健康人心肌酶谱的对照研究

发布时间：2018-07-20 12:48

【摘要】：目的观察心肌酶谱检测在精神分裂症患者的临床价值。方法采用生化酶水解法随机选取60例住院精神分裂症患者,70例门诊健康体检者,进行测定心肌酶谱:肌酸激酶(CK)、肌酸激酶同工酶(CK-MB)、乳酸脱氢酶(LDH)、天门冬氨酸氨基转移酶(AST)水平。结果精神分裂症组CK、CK-MB、LDH、ALT水平分别291.2±14.2、33.1±2.4、132.7±6.3、21.8±2.5 U/L,健康对照组CK、CK-MB、LDH、ALT水平分别58.2±8.1、12.9±2.1、130.6±5.1、21.2±2.2 U/L。精神分裂症组的CK、CK-MB,水平显著高于健康对照组(u值分别为112.397、50.626,P值均0.01),差异有统计学意义。精神分裂症的AST、LDH的水平(u值分别2.067、1.442,P值均0.05)差异无统计学意义。结论血清CK、CK-MB水平在精神分裂症急性发作中不能作为心肌梗塞的指标,它是病人病情发作、情绪激动、应急动作的反应。
[Abstract]:Objective to observe the clinical value of myocardial enzyme spectrum in schizophrenic patients. Methods 60 inpatients with schizophrenia and 70 healthy controls were randomly selected by biochemical enzyme hydrolysis. The levels of creatine kinase (CK), creatine kinase isoenzyme (CK-MB), lactate dehydrogenase (LDH) and aspartate aminotransferase (AST) were measured. Results the serum levels of CK CK-MBN LDH in schizophrenic patients were 291.2 卤14.2nil 33.1 卤2.4132.7 卤6.3 卤21.8 卤2.5UL / L, respectively, while those in the healthy controls were 58.2 卤8.1 卤12.9 卤2.1130.6 卤5.12UL / L, and those in healthy controls were 58.2 卤8.1and 12.9 卤2.1130.6 卤5.12U / L, respectively58.2 卤8.1 卤2.1130.6 卤5.12UL / L, respectively. The level of CKK-MBs in schizophrenia group was significantly higher than that in healthy control group (u = 112.397U = 50.626 P = 0.01), and the difference was statistically significant. There was no significant difference in the level of LDH in patients with schizophrenia (u value 2.067U 1.442 P = 0.05). Conclusion the level of CK-MB in serum can not be used as an index of myocardial infarction in acute episode of schizophrenia, it is the response of patient's state of illness, emotion and emergency action.
【作者单位】：浙江省黄岩第三人民医院;
【分类号】：R749.3

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