暴力犯罪嫌疑人与攻击行为精神分裂症患者血浆中5-羟色胺水平的比较

发布时间：2018-09-05 10:18

【摘要】：目的:研究暴力犯罪嫌疑人和有攻击行为的男性住院精神病患者血浆中5-羟色胺(5-hydroxy tryptamine,5-HT)的水平变化.方法:研究对象为男性暴力犯罪嫌疑人48例、具有攻击行为的男性住院精神分裂症患者37例、正常成年男性45例,年龄16~58岁.采用酶联免疫吸附(ELISA)试剂盒定量测定血浆中5-HT水平,统计分析各组血浆5-HT水平的差异.结果:暴力犯罪嫌疑人和有攻击行为的男性住院精神病患者血浆中5-HT水平均显著低于正常人(P0.01),而暴力犯罪嫌疑人血浆5-HT水平又显著低于有攻击行为的男性住院精神病患者(P0.01).结论:暴力犯罪嫌疑人和有攻击行为的男性精神病患者血浆中5-HT水平显著降低,监测有暴力倾向的罪犯和有攻击行为的精神病患者血浆5-HT水平变化,可能有助于预防和减少暴力行为的发生.
[Abstract]:Aim: to study the changes of plasma serotonin (5-hydroxy tryptamine,5-HT) levels in violent suspects and male inpatients with aggressive behavior. Methods: the subjects were 48 male suspects of violence, 37 male inpatients with aggressive behavior and 45 normal adult males aged 16 to 58 years. The level of 5-HT in plasma was measured quantitatively by Elisa (ELISA) kit and the difference of plasma 5-HT level in each group was statistically analyzed. Results: the plasma 5-HT levels of the violent suspects and the male inpatients with aggressive behavior were significantly lower than those of the normal controls (P0.01), while the plasma 5-HT levels of the violent suspects were significantly lower than those of the male inpatients with aggressive behavior (P0.01). Conclusion: the levels of 5-HT in the plasma of violent criminal suspects and male psychotic patients with aggressive behavior were significantly decreased, and the changes of plasma 5-HT levels in violent criminals and aggressive mental patients were monitored. It may help to prevent and reduce violence.
【作者单位】：佛山市第三人民医院精神科;佛山市第三人民医院检验科;暨南大学医学院生化教研室;
【基金】：佛山市科技发展专项资助项目(2012AA100161)
【分类号】：R749.3

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