电针对脑卒中后抑郁患者脑血流量的影响

发布时间：2018-09-16 21:31

【摘要】：目的研究电针对脑卒中后抑郁(PSD)患者局部脑血流量(r CBF)的影响。方法将21例脑卒中后抑郁患者随机分为电针组(n=11)和药物组(n=10)。电针组取双侧合谷、太冲穴,每天1次;药物组口服盐酸氟西汀分散片20 mg,每天1次,均连续治疗8周。患者分别于治疗前及治疗后2、4、8周使用汉密尔顿抑郁量表(HAMD)进行评定,治疗前及治疗后8周采用单光子发射计算机断层成像(SPECT)观察r CBF的变化。结果电针组治疗后2周时HAMD低于药物组(P0.05),而治疗后4周、8周时无显著性差异(P0.05)。治疗8周后,电针组r CBF较药物组改善更佳(P0.05)。结论电针治疗脑卒中后抑郁疗效明确,可能与改善卒中后脑灌注有关。
[Abstract]:Objective to study the effect of electroacupuncture on regional cerebral blood flow (r CBF) in (PSD) patients with post-stroke depression. Methods Twenty-one patients with post-stroke depression were randomly divided into electroacupuncture group (n = 11) and drug group (n = 10). In the electroacupuncture group, the bilateral Hegu and Taichong points were taken once a day, and in the drug group, fluoxetine hydrochloride dispersible tablets were taken orally once a day for 8 weeks. The patients were evaluated with Hamilton Depression scale (HAMD) before and after 2 weeks and 8 weeks after treatment. The changes of r CBF were observed by single photon emission computed tomography (SPECT) before and 8 weeks after treatment. Results the HAMD of electroacupuncture group was lower than that of drug group at 2 weeks after treatment (P0.05), but there was no significant difference at 4 weeks and 8 weeks after treatment (P0.05). After 8 weeks of treatment, r CBF in electroacupuncture group was better than that in drug group (P 0.05). Conclusion the effect of electroacupuncture on post-stroke depression may be related to the improvement of cerebral perfusion after stroke.
【作者单位】：浙江省人民医院康复医学科;
【基金】：浙江省卫生厅临床科研资助项目(No.2011KYA014)
【分类号】：R749.13

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