Morris水迷宫检测动物学习记忆水平的方法学
发布时间：2018-10-11 11:17
【摘要】：正阿尔茨海默病(AD)是现代医学的治疗难点,也是老年医学研究的热点。是目前神经生物学和神经药理学非常重要的研究内容。Morris水迷宫~([1])1981年初被设计并应用于学习记忆脑机制研究,目前已成为AD基础研究中评价动物学习记忆的经典方法。然而在国内外现有文献中,关于Morris水迷宫实验动物的选择、实验指标确定、数据统计等方面存在很大差异,这可能造成资源的浪费和实验成本的增高,导致实验结果和结
[Abstract]:Positive Alzheimer's disease (AD) is not only a difficult point in modern medicine, but also a hot spot in geriatrics. Morris water maze was designed and applied to study the brain mechanism of learning and memory at the beginning of 1981. It has become a classical method for evaluating animal learning and memory in the basic research of AD. However, in the existing literature at home and abroad, there are great differences in the selection of Morris water maze experimental animals, the determination of experimental indicators, data statistics and other aspects, which may lead to the waste of resources and the increase of experimental costs, resulting in experimental results and conclusions.
【作者单位】： 齐齐哈尔医学院机能实验教学中心;
【基金】：国家大学生创新创业项目基金项目(No.201411230046) 齐齐哈尔医学院院内基金项目(No.QY2014Z-12)
【分类号】：R749.16
[Abstract]:Positive Alzheimer's disease (AD) is not only a difficult point in modern medicine, but also a hot spot in geriatrics. Morris water maze was designed and applied to study the brain mechanism of learning and memory at the beginning of 1981. It has become a classical method for evaluating animal learning and memory in the basic research of AD. However, in the existing literature at home and abroad, there are great differences in the selection of Morris water maze experimental animals, the determination of experimental indicators, data statistics and other aspects, which may lead to the waste of resources and the increase of experimental costs, resulting in experimental results and conclusions.
【作者单位】： 齐齐哈尔医学院机能实验教学中心;
【基金】：国家大学生创新创业项目基金项目(No.201411230046) 齐齐哈尔医学院院内基金项目(No.QY2014Z-12)
【分类号】：R749.16
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