社会认知交互训练对双相情感障碍缓解期患者的影响
发布时间：2018-11-02 11:36
【摘要】：目的:观察社会认知交互训练(Social Cognition and Interaction Training,SCIT)对双相障碍缓解期患者临床症状及社会功能和认知功能的影响,为临床预防与干预提供依据。通过对社会认知交互训练(SCIT)和健康教育两种方式培训后,两组成员间在HAMD-17、YMRS上有无差异,探讨SCIT对于双相情感障碍患者症状的控制的帮助大小。通过对SCIT组和对照组在基线和8周末的认知功能及FAST变化的分析,探讨SCIT培训对双相情感障碍患者认知功能、整体功能的影响。通过详细分析FAST各个维度在培训前后的改变,探讨SCIT对于双相情感障碍患者在哪些维度上作用较为明显。本研究引进和调整后的SCIT培训方法,拓展了对于双相情感障碍患者的辅助治疗,希望本研究对于SCIT在中国双相情感障碍缓解期患者的辅助治疗上提供依据和数据支撑,并为有关双相情感障碍患者的后续研究及延伸到其他疾病种类提供理论参考。方法:采用前瞻性、随机分组、8周干预的方法,依据精神障碍统计与诊断手册第5版(DSM-5)的中双相障碍缓解期的诊断标准对符合入组的80名缓解期患者,随机方法分成2组,即SCIT组和对照组(健康教育组),两组各40名,其中SCIT组脱落5例,对照组脱落1例。采用汉密尔顿抑郁量表(HAMD-17)、杨氏躁狂量表(YMRS)、功能检测简版(FAST)、认知功能成套测验中文版(MCCB)等测验分别在基线和治疗8周给予评估,统计上采用IBM公司的SPSS软件23.0版本进行数据整理分析。计数资料选用χ2检验分析,采用百分比形式表示;若计量资料符合正态分布,则选用独立t检验、配对t检验进行分析,采用均数±标准差的形式表示;数据间的关联性,选用皮尔逊相关性分析,采用关联系数形式表示。以p0.05为统计具有显著性意义。结果:1.入组的两组被试者在人口资料方面,包括性别、年龄、婚姻状况、吸烟史、饮酒史、职业状况、教育年限,以及总病程年限、发病次数、家族史等一般社会和人口学资料差异未发现统计学意义(p㧐0.05)。2.两组被试者的HAMD-17和YMRS评分在入组时差异不具有统计学意。治疗8周末,SCIT组与对照组在HAMD-17、YMRS得分,SCIT组的减分更加明显,两者差异具有统计学意义(p0.05)。3.SCIT组和对照组在培训结束后,SCIT组在功能检测简版(FAST)得分上具有较明显的减分,两者差异具有统计学意义(p0.05)。4.SCIT组和对照组在培训结束后,认知功能方面的评估得分发现,SCIT组被试者在记忆力、逻辑推理能力、执行功能方面的功能得分均高于对照组,两组间差异具有统计学意义(p0.05)。结论:SCIT可能在双相障碍缓解期患者的临床症状的缓解、总体社会功能和认知功能相关改善起到相应作用,具有临床干预前景。
[Abstract]:Objective: to observe the effect of social cognitive interaction training (Social Cognition and Interaction Training,SCIT) on clinical symptoms, social function and cognitive function in patients with bipolar disorder in remission period, and to provide evidence for clinical prevention and intervention. After (SCIT) and health education were trained, there was no difference in HAMD-17,YMRS between the two groups, and the help of SCIT in controlling the symptoms of bipolar affective disorder patients was discussed. The effects of SCIT training on cognitive function and overall function of patients with bipolar affective disorder (bipolar affective disorder) were studied by analyzing the changes of cognitive function and FAST in SCIT group and control group at baseline and 8 weeks. Through the detailed analysis of the changes of each dimension of FAST before and after training, the effects of SCIT on the dimensions of bipolar affective disorder were discussed. This study introduces and adjusts the SCIT training method to expand the adjuvant treatment for bipolar affective disorder patients. It is hoped that this study can provide the basis and data support for the adjuvant treatment of bipolar affective disorder patients in China. It also provides a theoretical reference for the follow-up study of bipolar affective disorder and its extension to other diseases. Methods: according to the diagnostic criteria of the middle bipolar disorder (DSM-5) in the fifth edition of the Manual of Statistics and diagnosis of Mental Disorder (DSM-5), 80 patients were enrolled in the study according to the prospective, randomized and 8-week intervention. Methods randomly divided into two groups, SCIT group and control group (health education group), the two groups of 40 cases, SCIT group lost 5 cases, control group 1 case. Hamilton Depression scale (HAMD-17) and Young's mania scale (YMRS),) were used to test the cognitive function of (FAST),. The Chinese version of (MCCB) was evaluated at baseline and 8 weeks after treatment. Statistical data analysis using IBM SPSS software version 23. 0. The counting data were analyzed by 蠂 ~ 2 test, expressed in percentage form, if the measured data were normal distribution, the independent t test was used to analyze, and the mean 卤standard deviation was used to analyze the counting data. Pearson correlation analysis is used to express the correlation between data. P0.05 was statistically significant. The result is 1: 1. In terms of demographic data, the two groups included sex, age, marital status, smoking history, drinking history, professional status, education, total course of disease, number of cases. The difference of general social and demographic data, such as family history, was not statistically significant (p0.05). There was no significant difference in HAMD-17 and YMRS scores between the two groups when they entered the group. At the end of the 8th week of treatment, the scores of HAMD-17,YMRS in SCIT group and control group were significantly higher than those in SCIT group (p0.05). After training, the difference between 3.SCIT group and control group was significant (p0.05). The scores of (FAST) in the SCIT group were significantly lower than those in the control group (p0.05). After training, the scores of cognitive function in the 4.SCIT group and the control group were found to be significantly lower than those in the control group. The scores of memory, logical reasoning and executive function in SCIT group were significantly higher than those in control group (p0.05). Conclusion: SCIT may play a corresponding role in the relief of clinical symptoms, overall social function and cognitive function in patients with bipolar disorder in remission stage, and has the prospect of clinical intervention.
【学位授予单位】：天津医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R749.4
本文编号：2305896
[Abstract]:Objective: to observe the effect of social cognitive interaction training (Social Cognition and Interaction Training,SCIT) on clinical symptoms, social function and cognitive function in patients with bipolar disorder in remission period, and to provide evidence for clinical prevention and intervention. After (SCIT) and health education were trained, there was no difference in HAMD-17,YMRS between the two groups, and the help of SCIT in controlling the symptoms of bipolar affective disorder patients was discussed. The effects of SCIT training on cognitive function and overall function of patients with bipolar affective disorder (bipolar affective disorder) were studied by analyzing the changes of cognitive function and FAST in SCIT group and control group at baseline and 8 weeks. Through the detailed analysis of the changes of each dimension of FAST before and after training, the effects of SCIT on the dimensions of bipolar affective disorder were discussed. This study introduces and adjusts the SCIT training method to expand the adjuvant treatment for bipolar affective disorder patients. It is hoped that this study can provide the basis and data support for the adjuvant treatment of bipolar affective disorder patients in China. It also provides a theoretical reference for the follow-up study of bipolar affective disorder and its extension to other diseases. Methods: according to the diagnostic criteria of the middle bipolar disorder (DSM-5) in the fifth edition of the Manual of Statistics and diagnosis of Mental Disorder (DSM-5), 80 patients were enrolled in the study according to the prospective, randomized and 8-week intervention. Methods randomly divided into two groups, SCIT group and control group (health education group), the two groups of 40 cases, SCIT group lost 5 cases, control group 1 case. Hamilton Depression scale (HAMD-17) and Young's mania scale (YMRS),) were used to test the cognitive function of (FAST),. The Chinese version of (MCCB) was evaluated at baseline and 8 weeks after treatment. Statistical data analysis using IBM SPSS software version 23. 0. The counting data were analyzed by 蠂 ~ 2 test, expressed in percentage form, if the measured data were normal distribution, the independent t test was used to analyze, and the mean 卤standard deviation was used to analyze the counting data. Pearson correlation analysis is used to express the correlation between data. P0.05 was statistically significant. The result is 1: 1. In terms of demographic data, the two groups included sex, age, marital status, smoking history, drinking history, professional status, education, total course of disease, number of cases. The difference of general social and demographic data, such as family history, was not statistically significant (p0.05). There was no significant difference in HAMD-17 and YMRS scores between the two groups when they entered the group. At the end of the 8th week of treatment, the scores of HAMD-17,YMRS in SCIT group and control group were significantly higher than those in SCIT group (p0.05). After training, the difference between 3.SCIT group and control group was significant (p0.05). The scores of (FAST) in the SCIT group were significantly lower than those in the control group (p0.05). After training, the scores of cognitive function in the 4.SCIT group and the control group were found to be significantly lower than those in the control group. The scores of memory, logical reasoning and executive function in SCIT group were significantly higher than those in control group (p0.05). Conclusion: SCIT may play a corresponding role in the relief of clinical symptoms, overall social function and cognitive function in patients with bipolar disorder in remission stage, and has the prospect of clinical intervention.
【学位授予单位】：天津医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R749.4
【参考文献】
相关期刊论文 前10条
1 覃青;傅一笑;蒙华庆;向慧;黄颖;周于;张茂兰;蒋继泽;;编码测验及符号搜索测验作为认知内表型的稳定性研究[J];中国医药科学;2016年11期
2 董成文;王立凡;;元认知心理干预技术在双相情感障碍辅助治疗中的应用[J];校园心理;2015年04期
3 周新祥;龚文苹;裘林秋;王庆松;;连线测验在非痴呆型血管性认知损害患者中的应用研究[J];全科医学临床与教育;2015年03期
4 洪玲;邓红;;社会认知及交互训练对精神分裂症患者社会功能的影响[J];临床精神医学杂志;2015年01期
5 邓良华;刘青梅;唐立岩;许世欢;;社区综合干预对双相情感障碍患者社会功能和生活质量的影响[J];中国康复理论与实践;2014年07期
6 姚玲玲;;双相情感障碍认知功能的研究进展[J];医学理论与实践;2014年05期
7 王芳;;无抽搐电休克治疗(MECT)合并药物与单纯药物治疗双相情感障碍躁狂相临床对照研究[J];中国医药导刊;2013年05期
8 陀柠瑜;刘铁榜;;双相障碍患者社会认知功能的研究进展[J];国际精神病学杂志;2013年01期
9 ;编者的话[J];中国全科医学;2013年05期
10 时德菊;;综合性健康教育对首发精神分裂症病人作用的对照研究[J];全科护理;2012年33期
相关硕士学位论文 前1条
1 蔺华利;双相障碍的认知功能及心理社会功能损害特点的研究[D];第四军医大学;2006年
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