综合治疗脑卒中后抑郁患者的临床疗效

发布时间：2018-11-07 12:08

【摘要】：目的探讨综合治疗对脑卒中后抑郁(PSD)患者抑郁程度及日常生活能力改善的临床效果。方法 90例PSD患者随机分为对照1组、对照2组和观察组,每组30例,分别采用口服艾司西酞普兰、心理疏导+运动疗法、艾司西酞普兰+心理疏导+运动的综合疗法,治疗8 w后,采用汉密尔顿抑郁量表(HAMD)、日常生活能力(ADL)评分〔Barthel指数(BI)计分法〕评价患者的抑郁程度和日常生活自理能力。结果 3组治疗后HAMD、BI评分均优于治疗前(P0.01);观察组疗效均优于对照组(P0.05)。观察组总有效率,明显高于对照1组及对照2组(P0.05)。结论艾司西酞普兰联合心理疏导及运动的综合疗法可以明显降低卒中后抑郁患者HAMD评分及提高日常生活能力,且治疗抑郁总有效率明显优于单纯口服药物、或单纯心理疏导+运动治疗,具有显著临床疗效,值得临床推广。
[Abstract]:Objective to investigate the clinical effect of comprehensive treatment on depression and ADL in patients with (PSD) after stroke. Methods 90 patients with PSD were randomly divided into control group (n = 30), control group (n = 30) and control group (n = 30). After 8 weeks of treatment, the degree of depression and the ability to take care of daily living were evaluated by the Hamilton Depression scale (HAMD),) (ADL) score (Barthel index (BI) score). Results the HAMD,BI score of the three groups was better than that of the control group (P0.01), and the curative effect of the observation group was better than that of the control group (P0.05). The total effective rate of observation group was significantly higher than that of control group 1 and control group 2 (P0.05). Conclusion the combined therapy of Escitalopram combined with psychological dredging and exercise can significantly reduce the HAMD score and improve the daily living ability of the patients with post-stroke depression, and the total effective rate of treatment of depression is obviously better than that of oral medicine alone. Or simple psychological dredging exercise therapy, has a significant clinical effect, worthy of clinical promotion.
【作者单位】：河北大学;河北大学附属医院神经内科;
【分类号】：R749.13

【相似文献】