精神分裂症复发再入院影响因素及管理治疗研究

发布时间：2018-11-16 13:45

【摘要】：目的探讨精神分裂症复发再入院的影响因素,研究重性精神疾病管理治疗对精神分裂症复发再入院的干预效果。方法以2007年首次发病在本院住院治疗的368例精神分裂症患者为研究对象,使用生活事件量表(LES)、社会支持评定量表(SSRS)、自编调查表等对复发因素进行Logistic回归分析。在此基础上分为抗精神病药物开放治疗对照组(对照组,n=184)和重性精神疾病管理治疗干预组(干预组,n=184),观察5年来重性精神疾病管理治疗对精神分裂症复发再入院的影响。结果单因素回归分析显示,年龄、婚姻、家族史与精神分裂症复发再入院不相关(P0.05)。性别、未治疗的精神病期(DUP)、负性生活事件是复发再入院的危险性因素(P0.05);受教育程度、服药依从性、社会支持是精神分裂症复发再入院的保护性因素(P0.05)。多因素回归分析显示,服药依从性、社会支持、负性生活事件是复发再入院的主要影响因素(P0.05)。5年来干预组的复发再入院率较对照组下降(P0.05)。结论服药依从性、社会支持、负性生活事件是精神分裂症复发再入院的主要影响因素,重性精神疾病管理治疗干预是降低复发再入院率的重要措施。
[Abstract]:Objective to investigate the influencing factors of relapse readmission of schizophrenia and to study the effect of management therapy on relapse of schizophrenia. Methods 368 schizophrenic patients who were hospitalized in our hospital for the first time in 2007 were studied. The recurrence factors were analyzed by Logistic regression with (LES), Social support scale (SSRS),). On this basis, the patients were divided into two groups: open therapy control group (control group, nun184) and management intervention group (intervention group, nni184). To observe the effect of management therapy on relapse of schizophrenia in the past 5 years. Results univariate regression analysis showed that age, marriage and family history were not associated with relapse of schizophrenia (P0.05). Gender, untreated (DUP), negative life events were the risk factors of relapse readmission (P0.05). Education, drug compliance and social support were protective factors for relapse of schizophrenia (P0.05). Multivariate regression analysis showed that drug compliance, social support and negative life events were the main influencing factors of relapse readmission (P0.05). The relapse readmission rate of intervention group was lower than that of control group in the past 5 years (P0.05). Conclusion Drug compliance, social support and negative life events are the main factors influencing the relapse of schizophrenia. The intervention of management therapy is an important measure to reduce the relapse readmission rate.
【作者单位】：九江市第五人民医院精神科;
【基金】：江西省卫生厅2012年度科技计划(No.20123193)
【分类号】：R749.3

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