首发精神分裂症未治疗时间的变化及相关因素

发布时间：2018-12-11 04:47

【摘要】：目的探索首发精神分裂症患者的精神病未治疗时间(duration of unmedicted psychosis,DUP)的变化规律及其相关因素。方法对首都医科大学附属北京安定医院不同年份(1994、2004和2014年)首次发作的精神分裂症出院患者进行回顾性调查,描述DUP的变化。结果不同年份在首都医科大学附属北京安定医院就诊的精神分裂症首次发作的患者中,2014年就诊患者的DUP显著小于1994年和2004年,但后两者之间差异无统计学意义(P0.05)。2014年精神分裂症患者的DUP与其阳性与阴性症状量表(Positive and Negative Syndrome Scale,PANSS)减分率呈负相关。结论精神分裂症患者从发病到开始治疗的疾病未治疗时间明显缩短,其中学生、未婚和高学历群体的比例呈增加趋势,显示了我国精神卫生事业的发展和进步。
[Abstract]:Objective to investigate the changes of untreated psychotic time (duration of unmedicted psychosis,DUP) in patients with first-episode schizophrenia and its related factors. Methods retrospective investigation was carried out on the first episode of schizophrenia discharged from Beijing Anding Hospital affiliated to Capital Medical University in different years (1994 ~ 2004 and 2014), and the changes of DUP were described. Results the DUP in 2014 was significantly lower than that in 1994 and 2004 in the first episode of schizophrenia in Beijing Anding Hospital affiliated to Capital Medical University in different years. However, there was no significant difference between the latter two (P0.05). The DUP of schizophrenic patients in 2014 was negatively correlated with the negative and positive symptom scale (Positive and Negative Syndrome Scale,PANSS). Conclusion the untreated time of schizophrenic patients from the onset to the beginning of treatment is obviously shortened, and the proportion of students, unmarried and highly educated population is increasing, which indicates the development and progress of mental health in China.
【作者单位】：首都医科大学附属北京安定医院精神科北京脑重大疾病研究院精神分裂症研究所精神疾病诊断与治疗北京市重点实验室;北京中医药大学国医堂中医门诊部;
【基金】：北京市自然科学基金(7152069) 北京市科委首都临床特色应用研究专项(Z151100004015061)~~
【分类号】：R749.3

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