不同部位急性脑梗死与血管性认知障碍的相关性

发布时间：2019-03-14 12:06

【摘要】：目的:探究不同部位急性脑梗死与血管性认知障碍发生的关系。方法:选取2014年6月至2016年6月北京航天总医院神经内科收治的急性梗死患者212例,分为认知正常组、无痴呆型血管性认知障碍组、血管性痴呆组和混合型痴呆组,收集患者性别、年龄、既往史、个人史及认知、影像资料,分析不同梗死部位对认知功能的影响。结果:212例患者中,认知正常患者61例(28.77%)、无痴呆的血管性认知障碍患者74例(34.91%)、血管性痴呆患者56例(26.42%)、混合性痴呆患者21例(9.91%),多因素回归分析结果显示:额叶梗死增加无痴呆的血管性认知障碍及血管性痴呆发生风险(OR值分别为41.72和48.49);小脑梗死增加血管性痴呆及混合性痴呆发生风险(OR值分别为4.70和12.38);颞叶梗死则使得混合性痴呆发生风险显著增加(OR值56.98)。结论:本组脑梗死急性期内患者中约有71.3%的发生血管性认知障碍,其中额叶、颞叶及小脑梗死将增加其发生风险,值得临床关注并进行干预性治疗。
[Abstract]:Objective: to investigate the relationship between vascular cognitive impairment and acute cerebral infarction in different parts. Methods: 212 patients with acute infarction were selected from June 2014 to June 2016 in the Department of Neurology of Beijing Aerospace General Hospital. They were divided into normal cognitive group, non-dementia vascular cognitive impairment group, vascular dementia group and mixed dementia group. Sex, age, past history, personal history and cognitive, imaging data were collected to analyze the effects of different infarction sites on cognitive function. Results: among 212 patients, 61 (28.77%) had normal cognition, 74 (34.91%) had vascular cognitive impairment without dementia, and 56 (26.42%) had vascular dementia. There were 21 patients (9.91%) with mixed dementia. Multivariate regression analysis showed that frontal lobe infarction increased the risk of vascular cognitive impairment and vascular dementia without dementia (OR = 41.72 and 48.49, respectively). Cerebellar infarction increased the risk of vascular dementia and mixed dementia (OR = 4.70 and 12.38, respectively), and temporal lobe infarction significantly increased the risk of mixed dementia (OR = 56.98). Conclusion: about 71.3% of the patients with acute cerebral infarction have vascular cognitive impairment, and frontal, temporal and cerebellar infarction will increase the risk of vascular cognitive impairment. It is worthy of clinical attention and intervention therapy. [WT5 "HZ] conclusion:\?
【作者单位】：北京航天总医院神经内科;
【分类号】：R749.13

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