焦虑障碍危险因素病例对照研究

发布时间：2019-05-05 11:47

【摘要】：目的:探讨焦虑障碍及其中强迫症、恐怖症发生的危险因素。方法:以北京市精神障碍流行病学调查使用复合性国际诊断交谈表(CIDI-3.0)所获得的社区焦虑障碍患者150例、恐怖症患者103例、强迫症患者60人作为三个独立的病例组;选择调查所获正常人群737人作为共用的对照组,进行病例对照研究。采用多因素非条件logistic回归分析焦虑障碍的危险因素。结果:焦虑障碍的危险因素为父母物质剥夺(OR=3.95,95%CI:1.20~12.95)和父母让其做过危险事情(OR=2.06,95%CI:1.22~3.51)。强迫症的危险因素为女性(OR=2.31,95%CI:1.15~4.62)、农村居住地(OR=4.49,95%CI:1.48~13.64)、家庭收入不能满足日常需要(OR=2.15,95%CI:1.14~4.07)。恐怖症的危险因素为父母物质剥夺(OR=5.04,95%CI:1.43~17.82)。结论:影响焦虑障碍及其中强迫症和恐怖症发生的危险因素主要为童年期的不良经历,包括不良的家庭生活环境和父母养育方式。
[Abstract]:Objective: to explore the risk factors of anxiety disorder and obsessive-compulsive disorder (OCD) and phobia. Methods: a total of 150 patients with community anxiety disorder, 103 patients with phobia and 60 patients with obsessive-compulsive disorder (OCD) were selected from the Beijing Mental Disorder Epidemiology Survey (CIDI-3.0). A case-control study was conducted with 737 normal subjects as a common control group. Multivariate non-conditional logistic regression was used to analyze the risk factors of anxiety disorder. Results: the risk factors of anxiety disorder were parental material deprivation (OR=3.95,95%CI:1.20~12.95) and parents' having made them do dangerous things (OR=2.06,95%CI:1.22~3.51). The risk factors for obsessive-compulsive disorder were female (OR=2.31,95%CI:1.15~4.62), rural residence (OR=4.49,95%CI:1.48~13.64), and family income was not adequate for daily needs (OR=2.15,95%CI:1.14~4.07). The risk factor for phobia is parental material deprivation (OR=5.04,95%CI:1.43~17.82). Conclusion: the main risk factors of anxiety disorder, obsessive-compulsive disorder and phobia are bad childhood experiences, including poor family living environment and parental rearing style.
【作者单位】：北京大学第六医院;北京大学精神卫生研究所;卫生部精神卫生学重点实验室(北京大学);
【分类号】：R749.72

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