宁夏川区、山区健康人群白破抗体水平调查

发布时间：2018-01-15 04:32

本文关键词：宁夏川区、山区健康人群白破抗体水平调查　出处：《现代预防医学》2015年07期 　论文类型：期刊论文

【摘要】：目的了解宁夏川区、山区不同类型健康人群白喉及破伤风抗体水平,为制定免疫策略提供依据。方法按照不同区域类型采用多阶段整群抽样选择调查对象,应用酶联免疫吸附试验(ELISA)对健康人群白喉及破伤风Ig G抗体进行检测。结果共调查920例(川区县520例,山区县400例)。白破抗体阳性率均为川区县高于山区县(白喉:χ2=21.47,P0.01;破伤风:χ2=11.71,P0.01),高年龄组人群白破抗体阳性率较低,山区女性健康人群白破抗体阳性率均高于男性(白喉:χ2=48.70,P0.01;破伤风:χ2=60.32,P0.01),川区汉族人群白喉抗体阳性率高于回族(χ2=4.91,P0.01),山区白破抗体阳性率均为汉族高于回族(白喉:χ2=84.58,P0.01;破伤风:χ2=107.68,P0.01)。结论宁夏健康人群白喉及破伤风抗体水平较低,且山区人群更为明显,随年龄的增长,免疫力衰减,易感人群数量增多,建议加强对成人,尤其是男性及回族等白破免疫抵抗力较弱人群的百白破及白破疫苗的免疫工作。
[Abstract]:Objective to understand the level of diphtheria and tetanus antibody in different types of healthy people in Sichuan and mountainous areas of Ningxia, and to provide the basis for making immunization strategy. Methods according to different regional types, multi-stage cluster sampling was used to select the survey subjects. Elisa was used to detect IgG antibody to diphtheria and tetanus in healthy population. Results 920 cases (520 cases in Sichuan district) were investigated. The positive rate of antibody against PPD was higher in Sichuan county than that in mountain county (蠂 2 + 21. 47%, P 0. 01), and the positive rate was higher in Sichuan county than that in mountain county (蠂 2 + 21. 47%, P 0. 01). For tetanus, the positive rate of CDA was lower in the older group than in the healthy group. The positive rate of the antibody was higher in the healthy women than in the male (蠂 2: 48.70, 蠂 2: 48.70, 蠂 2 = 48.70). P0.01; The positive rate of diphtheria antibody in Han nationality in Sichuan area was higher than that in Hui nationality (蠂 ~ 2 ~ 2 ~ (4.91) P ~ (0.01)). The positive rate of the antibody was higher in the Han nationality than in the Hui nationality (蠂 2: 84.58%, P 0.01). Conclusion the level of antibody to diphtheria and tetanus in healthy population of Ningxia is lower than that in mountain area. The number of susceptible population increased. It is suggested to strengthen the immunization of white tetanus and its vaccine to adults, especially to male and Hui people.
【作者单位】：宁夏疾病预防控制中心免疫规划科;
【分类号】：R186
【正文快照】： 截至2013年,宁夏已连续30年无白喉病例报告,新生儿破伤风虽每年仍有病例报告,但发病率呈现下降趋势。宁夏因地势差异分为川区和山区[1],不同地域居民收入分配及生产生活方式区别较大,为掌握目前宁夏不同地域健康人群白喉、破伤风免疫水平,科学预测该病发病趋势,针对性制定免疫

【参考文献】