伊宁县农村5岁以下维吾尔族儿童出生缺陷流行病学调查

发布时间：2018-02-08 08:27

本文关键词： 出生缺陷五岁以下维吾尔族　出处：《新疆医科大学》2009年硕士论文　论文类型：学位论文

【摘要】： 目的:了解伊宁县农村的5岁以下维吾尔族儿童通过肉眼观察即可诊断的出生缺陷的分布情况,探索可能的影响因素。方法:本研究依据全国妇幼卫生监测办公室提供的《主要先天畸形诊断手册》,北京医科大学出版的《出生缺陷诊断图谱》中的诊断标准对伊宁县农村5岁以下维吾尔族儿童进行调查。调查员根据各乡计划生育专干提供的资料,对本次调查的对象进行入户问卷调查。用1:2配比的病例对照研究方法,分析出生缺陷的危险因素。资料用条件Logistic回归方法进行单因素和多因素分析。结果:(1)本次调查存活的出生缺陷儿童共41人,发生率为33.3/万,男性发生率为34.8/万,女性为31.8/万,男女发生率之比为1.09:1。(2)出生缺陷的发生顺位为唇腭裂,短肢畸形、唇裂,先天性髋关节脱位,脊柱裂、唐氏综合症。(3)单因素分析有统计学意义的因素为:产次、孕次、怀孕年龄、孕期疾病、父母亲受教育程度、父亲饮酒、家族遗传史。多因素分析有统计学意义的为:产次、怀孕年龄、家族遗传史。结论:本次调查虽然总的发生率低于国家监测报道,但高于新疆妇幼监测数据,发生顺位也与报道不一致,因此应针对发生率高的出生缺陷种类,加强孕期保健的管理,广泛开展优生和保健知识宣传,以进一步降低出生缺陷的发生率。
[Abstract]:Objective: to investigate the distribution of birth defects diagnosed by naked eye in Uygur children under 5 years old in the countryside of Yining County. Methods: according to the diagnosis Manual of main congenital malformations provided by the National Maternal and Child Health Surveillance Office and the Diagnostic Diagnostic Map of birth defects published by Beijing Medical University. Uygur children under 5 years of age were investigated in the rural areas of Yining County. According to the information provided by family planning professionals in various townships, A household questionnaire survey was conducted on the subjects of this survey. A case-control study with 1: 2 matching was used. The risk factors of birth defects were analyzed. The data were analyzed by conditional Logistic regression method. Results: there were 41 surviving children with birth defects, the incidence rate was 33.3 / 10 000, the incidence of male was 34.8 / 10 000, and that of female was 31.8 / 10 000. The incidence of birth defects was in the order of cleft lip and palate, short limb deformity, cleft lip, congenital dislocation of hip joint, spina bifida, Down's syndrome. Diseases during pregnancy, education level of parents, father's drinking, family genetic history. Multivariate analysis was statistically significant as follows: birth, pregnancy age, family genetic history. Conclusion: although the overall incidence of this survey is lower than the national surveillance report, But it is higher than the data of maternal and child monitoring in Xinjiang, and the sequence of occurrence is inconsistent with the report. Therefore, it is necessary to strengthen the management of health care during pregnancy and widely promote the knowledge of eugenics and health care in view of the types of birth defects with high incidence. To further reduce the incidence of birth defects.
【学位授予单位】：新疆医科大学
【学位级别】：硕士
【学位授予年份】：2009
【分类号】：R174;R181.3

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