人感染H7N9禽流感的流行特征

发布时间：2018-03-15 20:15

本文选题：禽流感　切入点：HN亚型　出处：《中华医院感染学杂志》2015年03期 　论文类型：期刊论文

【摘要】：目的对我国发生人感染H7N9禽流感的流行病学特点进行分析,为H7N9禽流感的预防控制提供依据。方法人感染H7N9禽流感确诊132例的病例相关数据来源于2013年3-5月中国国家卫生和计划生育委员会网站(http://www.chinapop.gov.cn/yjb/h7n9/list.shtml)和我国台湾地区卫生署疾管局网站(http://www.cdc.gov.tw/),通过Excel 2007软件进行统计分析,总结其发病地点、时间、患者性别和年龄分布、临床症状轻重等因素。结果 132例H7N9禽流感确诊病例基本为散发状态,绝大多数发生在华东地区,浙江、上海和江苏3省市较多,各占34.85%、25.00%、20.45%;病例数在前3周呈上升趋势,第3周峰值达47例,随后逐渐下降,至第6周后基本无新增确诊病例;男女性别比为2.34∶1,男性病例远多于女性;年龄分布在4~91岁,以中老年人为主,45岁确诊病例占75.76%;确诊病例大部分表现为重症或病死,该两者占76.52%,其中死亡38例,病死率达28.79%。结论人感染H7N9禽流感确诊病例的流行病学特征与其他禽流感例如H5N1显然不同,具体原因有待于进一步研究确定。
[Abstract]:Objective to analyze the epidemiological characteristics of human infection with H7N9 avian influenza in China. Methods data related to 132 confirmed cases of human infection with H7N9 avian influenza were obtained from the website of the National Health and Family Planning Commission of China on 2013 at http: / / www.chinapop.gov.cnryjbrh7n9rlist.shtml. On the website of the Administration, http: / / www.cdc.gov.twr.w.r.uk, through the Excel 2007 software, to carry out statistical analysis. Results 132 confirmed cases of H7N9 avian influenza were basically sporadic, most of which occurred in eastern China and Zhejiang. There were more cases in Shanghai and Jiangsu provinces, accounting for 34.85% and 25.00% respectively, the number of cases showed an upward trend in the first three weeks, the peak value reached 47 cases in the third week, then decreased gradually, and after 6 weeks there were almost no new confirmed cases, the ratio of male to female was 2.34: 1, and the male case was much more than that of female. The age distribution ranged from 4 to 91 years old, with the majority of the middle-aged and the elderly accounting for 75.76.The majority of the confirmed cases were severe or dead, and the two accounted for 76.52, of which 38 were dead. Conclusion the epidemiological characteristics of confirmed cases of human infection with H7N9 avian influenza are obviously different from those of other avian influenza viruses such as H5N1, and the specific reasons need to be further studied.
【作者单位】：浙江省肿瘤医院检验科;浙江省医学科学院病毒病研究所;
【基金】：浙江省自然科学基金资助项目(Y2100449) 浙江省医药卫生科技计划基金资助项目(2014KYA039)
【分类号】：R511.7;R181.3

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