一种衣物消毒洗衣露的消毒相关性能试验观察

发布时间：2018-05-07 05:43

本文选题：衣物消毒洗衣露 + 苯扎溴铵　；参考：《中国消毒学杂志》2017年08期

【摘要】：目的观察一种衣物消毒洗衣露的杀菌效果及其毒性,为实际应用提供科学依据。方法采用悬液和载体定量杀菌试验和毒理学试验方法,对该衣物消毒洗衣露杀菌效果和毒性进行实验研究。结果用含苯扎溴铵860 mg/L的衣物消毒洗衣露作用2.5 min,对悬液内大肠杆菌和金黄色葡萄球菌杀灭对数值均5.00;对白色念珠菌杀灭对数值均4.00。在同样条件下,该衣物消毒洗衣露对载体上大肠杆菌和金黄色葡萄球菌作用2.5 min,对白色念珠菌作用5 min杀灭对数值均3.00。该衣物消毒洗衣露对小鼠经口急性毒性试验LD50值均5 000 mg/(kg·bw),对小鼠骨髓嗜多染红细胞微核试验结果为阴性,一次接触动物完整皮肤刺激性试验结果为无刺激性。结论该衣物消毒洗衣露对细菌繁殖体和真菌具有良好的杀灭效果,属于实际无毒级物质,对完整皮肤无刺激性。
[Abstract]:Objective to observe the bactericidal efficacy and toxicity of a clothing disinfectant laundry lotion and to provide scientific basis for its practical application. Methods suspension and carrier quantitative germicidal test and toxicological test were used to study the bactericidal efficacy and toxicity of the clothings disinfectant laundry lotion. Results the logarithmic values of Escherichia coli and Staphylococcus aureus in suspension were 5.00 and 4.00 for Candida albicans. Under the same conditions, the disinfectant laundry lotion was exposed to Escherichia coli and Staphylococcus aureus on the carrier for 2.5 mins and to Candida albicans for 5 min. The LD50 values of the acute toxicity test on mice were 5 000 mg/(kg BWN, but the micronucleus test results of bone marrow polychromatic erythrocytes in mice were negative, and the irritation results of one contact with the intact skin of animals were no irritation. Conclusion the disinfectant laundry lotion has a good killing effect on bacteria and fungi. It belongs to non-toxic substance and has no irritation to intact skin.
【作者单位】：山西省疾病预防控制中心;
【分类号】：R187.2

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