2010年浙江省居民甲状腺结节患病状况及相关因素

发布时间：2018-05-19 21:08

本文选题：甲状腺结节 + 危险因素　；参考：《卫生研究》2017年06期

【摘要】：目的了解浙江省居民的甲状腺结节患病现况,探讨甲状腺结节的相关危险因素。方法采用分层整群抽样方法,于2010年3—12月抽取浙江省22个县区,对18 956名常住人口和生活3年以上外来人员进行问卷调查(包括一般情况、生活及饮食习惯、自身健康状况及疾病史等),并进行甲状腺B超和水碘、盐碘、尿碘等检测,计算不同地区不同人群甲状腺结节患病率,描述甲状腺结节相关因素的分布水平,并运用Logistic回归分析可能影响甲状腺结节的危险因素。结果浙江省居民甲状腺结节患病率为21.78%(4129人),其中单发结节患病率为11.75%(2227人),高于多发结节的10.03%(1902人)(χ~2=281.44,P0.05);男性甲状腺结节患病率为16.60%(1324人),低于女性的25.59%(2795人)(χ~2=218.60,P0.05),城市居民为23.62%(2226人),高于农村居民的19.97%(1903人)(χ~2=922.53,P0.05),且均随年龄增长而逐渐升高(χ~2=36.99,P0.05);沿海、次沿海和内陆地区甲状腺结节患病率依次为25.05%(1927人)、20.27%(1343人)和18.52%(859人)(χ~2=85.84,P0.05);文化程度高、常吃海产品、生气频率高、有甲状腺疾病患病史[OR(95%CI)分别为1.11(1.06~1.16)、1.34(1.18~1.51)、1.12(1.03~1.22)和2.21(1.51~3.24)]及碘营养水平缺乏是浙江省居民甲状腺结节患病的危险因素。结论 2010年浙江省居民甲状腺结节女性患病率高于男性,且随年龄增长而逐渐升高;中老年人群应是甲状腺结节防治工作的重点对象;儿童甲状腺结节患病率虽较低,但因为其发展为恶性的危险性高,应引起重视;文化程度高、有食用海产品习惯、生气频率高、有甲状腺疾病患病史、碘营养水平缺乏可能是人群甲状腺结节发生的危险因素。
[Abstract]:Objective to investigate the prevalence and risk factors of thyroid nodules in Zhejiang Province. Methods the stratified cluster sampling method was used to select 22 counties and districts in Zhejiang Province from March to December 2010. A questionnaire survey was conducted among 18 956 permanent residents and foreigners living for more than 3 years (including general situation, life and eating habits). The incidence of thyroid nodules in different population in different areas was calculated, and the distribution level of factors related to thyroid nodules was described by detecting thyroid B ultrasound, water iodine, salt iodine, urinary iodine and so on. Logistic regression analysis was used to analyze the risk factors of thyroid nodules. Results the prevalence rate of thyroid nodules in Zhejiang Province was 21.78. The prevalence rate of thyroid nodules was 11.75 / 2227, which was higher than that of 10.03 / 1902 with multiple nodules (蠂 ~ 2 / 2 / 281.44 / P 0.05). The prevalence rate of thyroid nodules in men was 16.600.1324, which was lower than that in women's (25.592,795) (蠂 ~ 2 / 22 / 218.60 / P 0.05) and 23.622226 / 2 026 in urban residents. The number of people living in the countryside was 19.97% higher than that of the rural residents (蠂 2 / 922.53 / P 0.05), and all of them gradually increased with the increase of age (蠂 2 / 2 / 36.99 / P / 0.05; along the coast, The incidence of thyroid nodules in the coastal and inland areas was 25.05 and 18.52 respectively (25.05, 19.27 and 1343, respectively) and 18.52, 859 (蠂 ~ (2 +), 85.84, P 0.05), with a high level of education, frequent consumption of seafood, and high frequency of life, and the incidence of thyroid nodules in coastal and inland areas was higher than that in other regions, and the incidence of thyroid nodules in coastal and inland areas was 25.05 and 18.52, respectively. The history of thyroid disease [ORY95CII = 1.111.06 / 1.16 / 1.341.181.18 / 1.51 / 1.22] and iodine deficiency were risk factors of thyroid nodule in Zhejiang province. Conclusion the prevalence rate of thyroid nodules in Zhejiang Province in 2010 was higher than that in men, and the prevalence rate of thyroid nodules in children was low, and the prevalence rate of thyroid nodules in middle and old people should be the focus of the prevention and treatment of thyroid nodules. However, due to its high risk of malignancy, attention should be paid to its high level of education, high habit of edible seafood, high frequency of life, history of thyroid disease, and iodine deficiency may be the risk factors of thyroid nodule in the population.
【作者单位】：浙江省疾病预防控制中心环境与职业卫生所;
【基金】：浙江省科技厅重大专项(No.2009C03010-1)
【分类号】：R181.3;R581

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