云南省某地艾滋病病毒和其他性传播感染的流行病学研究

发布时间：2018-05-24 16:25

本文选题：暗娼 + 矿工　；参考：《东南大学》2006年硕士论文

【摘要】： 研究目的:(1)估计云南省个旧市暗娼及矿工的HIV/ STIs感染率;(2)分析该地暗娼及矿工HIV / STIs的可能危险因素;(3)评价该地暗娼及矿工HIV相关知识、态度和行为;(4)描述该地暗娼及矿工的流动情况。研究方法:2005年12月~2006年1月,在云南省个旧市,分别以普查方式和方便抽样的方法,招募并调查了暗娼239人、矿工526人。对所有研究对象进行一对一面对面访谈方式进行匿名问卷调查,同时采集血标本检测HIV(ELISA法初筛,蛋白印迹法确认)、梅毒螺旋体(RPR法初筛、TPPA法确认)、HSV-2(ELESA法),采集女性宫颈分泌物标本和男性尿标本检测淋病奈瑟菌和衣原体(复合PCR法)、采集女性阴道分泌物标本检测滴虫(湿片法镜检),对所有研究对象的尿液标本进行吗啡检测(ACON MOP试纸法)。研究结果:1、暗娼人群:(1)暗娼HIV感染率为18.6%,其中,吸毒暗娼感染率55.4%,非吸毒暗娼感染率为1.8%。多因素logistic回归分析发现,吸毒(OR=39.94)、经常变换工作场所(OR=6.19)是当地暗娼感染HIV的主要的危险因素;随着当地暗娼年龄的增加,HIV感染人数呈上升趋势(OR=1.17)。(2)5种STIs的总感染率为74.9%。其中梅毒、单纯疱疹病毒2型(HSV-2)、淋病奈瑟菌、沙眼衣原体、滴虫感染率分别为3.8%,64.6%,4.4%,15.3%,4.8%。HIV(OR=4.73)感染和安全套使用(OR=0.46)是影响STIs的因素。(3)29.4%感染2种或2种以上病原体。(4)27.2%的暗娼自我报告使用过毒品,其中90.8%注射过毒品。暗娼与非付费性伴和付费性伴不持续使用安全套的比例分别为76.16%和32.77%(χ_(CMH)~2=136.3955,df=4,P0.0001)。(5)80.7%的暗娼在本地连续居住半年以上,68.1%的暗娼连续居住1年以上,36.13%的暗娼最近1年换过工作场所,20.8%的暗娼同时在2个以上服务场所工作。暗娼换工作场所和换工作城市的原因不同(χ_(CMH)~2=28.9275,df=3,P0.0001)。(6)通过暗娼收集到11.4%的付费性伴是矿工。2、矿工人群:(1)矿工HIV感染率为0.6%。4种STIs的总感染率为18.3%,其中,HSV-2、梅毒、淋病奈瑟菌、沙眼衣原体的感染率分别为13.29%、1.4%、0.2%和5.16%。1.98%的矿工合并感染2种或2种以上HIV/STIs。多因素分析发现多性伴(OR=1.96)和吸毒(OR=3.78)是HIV/STIs感染的危险因素。(2)有过性行为的对象中,58.6%与2个及2个以上的人发生过性关系,16.1%有过商业性行为,84.9%最近1年从不使用安全套。在商业性行为中,64.3%在嫖娼时从不使用安全套。52.7%在个旧市区找暗娼。29.5%的矿工与他人共用过剃须刀。HIV三种传播途径的正确回答率为60.05%,所有艾滋病相关问题正确回答率为3.35%。(3)97.34%的矿工是离家外出打工者,其中42.38%换过工作城市。结论:目前云南省个旧市暗娼人群中HIV/STIs流行形势严重,合并感染率高,给当地HIV/STIs的控制带来严峻挑战。本研究发现该地暗娼HIV感染的主要因素是吸毒和场所之间流动。无保护性
[Abstract]:Objective: to estimate the HIV/ STIs infection rate of female sex workers and miners in Gejiu City, Yunnan Province (2) to analyze the possible risk factors of HIV / STIs among prostitutes and miners in Gejiu City, Yunnan Province. Attitude and behavior describing the movement of prostitutes and miners in the area. Methods: from December 2005 to January 2006, 239 prostitutes and 526 miners were recruited and investigated in Gejiu City, Yunnan Province by means of general survey and convenient sampling. An anonymous questionnaire survey was conducted on all the subjects by one-to-one face-to-face interview, and blood samples were collected and tested by HIV(ELISA method. Western blotting method was used to identify Neisseria gonorrhoeae and Treponema pallidum rPR method was used to detect HSV-2ELESA method. Gonorrhoeae and chlamydia were detected in female cervical secretions and male urine samples (combined with PCR method), and female vaginal secretions were collected for detection of Chlamydia gonorrhoeae and Chlamydia gonorrhoeae. Trichomonas was detected by wet film method, and the urine samples of all the subjects were tested for morphine by ACON MOP test paper method. The HIV infection rate of CSW was 18.6. among them, the infection rate of CSW was 55.4%, and that of non-drug-using CSW was 1.80.The results showed that the infection rate of CSW was 18.6%, and the infection rate of CSW was 55.4% and 1.8% respectively. Multivariate logistic regression analysis showed that the main risk factors of HIV infection in local prostitutes were 39. 94% of drug users and 6. 19% of workplace changes, and the total infection rate of 5 STIs species was 74.9 with the increase of age of local prostitutes. Among them, syphilis, herpes simplex virus type 2 HSV-2, Neisseria gonorrhoeae, Chlamydia trachomatis, The infection rate of trichomonad was 3.84.64.33.The infection rate of STIs and condom use were 3.84.34.73) and 0.46% of them were infected with two or more pathogens. 27.2% reported that they had used drugs, and 90.8% of them had injected drugs. The proportion of illegal sex workers, non-paying sex partners and paying sex partners who do not use condoms continuously is 76.16% and 32.77% respectively (蠂 / CMH / T 2136.3955 / dffc4). 80.7% of illegal sex workers live continuously in the local area for more than six months and 68.1% live continuously for more than one year or more. 36.13% of secret sex workers have changed workplaces for more than one year in the last year. 20. 8% of the prostitutes work in more than 2 service places at the same time. Among them, 11.4% of paid sex partners collected by CSW were miner. 2) the HIV infection rate of miner was 0.6.4 STIs, and the total infection rate of miner was 18.33%, including HSV-2, syphilis, Neisseria gonorrhoeae. The infection rate of chlamydia trachomatis was 13.29% and 5.16.1.98% respectively. Multivariate analysis showed that polysexual partner OR1.96) and drug addicts OR3.78) were the risk factors of HIV/STIs infection. 58.6% of the subjects who had sexual intercourse with 2 or more people had sexual relations with two or more people. 84.9% had never used condoms in the last year. In commercial sex, 64.3% never used condoms while visiting prostitutes. 52.7% of the miners in Gejiu city district used secret sex workers. 29.5% of miners had shared razor .HIV with others. The correct answer rate of all AIDS-related questions was 60.055.The correct answer rate of all AIDS related questions was 64.5%. 3.35. 397.34% of the miners left their homes to work, 42.38% of them changed jobs. Conclusion: the prevalence of HIV/STIs among female sex workers in Gejiu City of Yunnan Province is serious, and the co-infection rate is high, which brings serious challenge to the control of HIV/STIs. In this study, we found that the main factors of HIV infection in prostitutes were drug abuse and mobility between places. Unprotected
【学位授予单位】：东南大学
【学位级别】：硕士
【学位授予年份】：2006
【分类号】：R181.3

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