武汉市成人胃肠疾病流行病学调查研究

发布时间：2018-06-06 05:52

  本文选题：胃肠疾病 + 罗马Ⅱ标准　； 参考：《华中科技大学》2008年硕士论文

【摘要】： 目的:通过调查武汉市成年人胃肠疾病的患病率,探讨胃肠疾病的危险因素。 方法:以随机分层整群抽样的方法选择调查地点,在选取的城乡调查点,以单层随机抽样方法从所选调查点的居民名单中抽取18到80岁成年人共3600人。调查问卷为简化的ROME II组合问卷和返流性疾病问卷。按照ROME II标准对各种胃肠疾病进行诊断。计算胃肠疾病患病率并用多元Logistic回归分析探讨胃肠疾病的危险因素。资料经Epidata3.02建库并用SAS8.2统计软件进行统计学分析。 结果:1、调查合格问卷3567份,既往胃肠疾病患病率为:胃食管反流病2.16%、消化不良6.57%、吞咽困难0.73%、胃炎11.21%、消化性溃疡4.74%、胆囊疾病2.97%、肠易激综合征0.20%、炎症性肠病2.16%和食管癌胃癌0.06%。 2、ROME II标准下胃肠疾病患病率为17.41%,其中GERD的患病率为2.94%,反刍综合征患病率为1.26%,功能性消化不良患病率为5.07%,吞气症患病率为2.47%,IBS患病率为4.12%,功能性腹胀患病率为4.29%,功能性便秘患病率为7.04%,功能性腹泻患病率为0.73%。 3、不同性别、地区和年龄间胃肠疾病患病率存在差异。女性患病率高于男性(18.90%15.57%,P=0.0092),农村患病率高于城市(20.74%13.95%,P0.0001),胃肠疾病的患病率有随着年龄升高而升高的趋势(P0.0001)。患有两种以上胃肠疾病的人占患有胃肠疾病人群的37.38%。 4、在城市,学历、总的健康状况、从事日常生活的能力、精神状态和家族遗传史是胃肠疾病的危险因素,调整OR值分别为0.861、1.610、1.254、1.292和1.427。在农村,性别、年龄、总的健康状况、工作中的劳动强度、精神状态和胃肠疾病家族史是胃肠疾病的危险因素,调整OR值分别为1.370、1.154、1.312、1.121、1.186和1.558。 结论:武汉市罗马Ⅱ标准诊断的胃肠疾病患病率为17.41%,男性15.57%,女性18.90%,城区13.95%,农村20.74%。患病率女性高于男性,农村高于城市。胃肠疾病的患病率有随着年龄升高而升高的趋势;胃肠疾病有疾病重叠现象;胃肠疾病各病种的患病率低于我国其它地区;胃肠疾病患者的就诊情况不容乐观;居民的生活行为方式与胃肠疾病的发病密切相关,胃肠疾病的发生是多种因素共同作用的结果。
[Abstract]:Objective: to investigate the prevalence of gastrointestinal diseases among adults in Wuhan, and to explore the risk factors of gastrointestinal diseases. A single-layer random sampling of 3600 adults aged 18 to 80 from a list of residents at selected sites was carried out. The questionnaire consisted of a simplified rome II questionnaire and a reflux disease questionnaire. Various gastrointestinal diseases were diagnosed according to rome II criteria. The prevalence of gastrointestinal diseases was calculated and the risk factors of gastrointestinal diseases were analyzed by multivariate logistic regression analysis. The data were analyzed by using statistical software SAS8.2 and Epidata 3.02. Results: 3567 qualified questionnaires were obtained. The prevalence rates of gastrointestinal diseases were: gastroesophageal reflux disease 2.16, dyspepsia 6.57, dysphagia 0.73, gastritis 11.21, peptic ulcer 4.74g, gallbladder disease 2.97cm, irritable bowel syndrome 0.20, inflammatory bowel disease 2.16% and esophageal carcinoma and stomach cancer 0.066.2 ROME II. The prevalence rate of GERD was 2.94, ruminant syndrome 1.26, functional dyspepsia 5.07, GERD 2.47 IBS 4.12, functional abdominal distension 4.29 and functional constipation 7.04, GERD 2.94, ruminant syndrome 1.26, functional dyspepsia 5.07, IBS 4.12, functional abdominal distension 4.29, functional constipation 7.04. The prevalence of active diarrhea was 0.73. 3, different sex, There were differences in the prevalence of gastrointestinal diseases between regions and ages. The prevalence of gastrointestinal diseases in women was higher than that in men (18.90) and in rural areas (P _ (0.0001). The prevalence rate of gastrointestinal diseases in rural areas was higher than that in urban areas (P _ (0.0001) and P _ (0.0001). People with more than two kinds of gastrointestinal diseases account for 37.38.4% of the population with gastrointestinal diseases. In cities, education, general health status, ability to engage in daily life, mental state and family genetic history are risk factors for gastrointestinal diseases. The adjusted OR values were 0.861 / 1.610 / 1.254 / 1.292 and 1.427, respectively. In rural areas, sex, age, general health status, labor intensity at work, mental status and family history of gastrointestinal disease are risk factors for gastrointestinal disease. The adjusted OR values were 1.370, 1.154, 1.3121.121, 1.186 and 1.558.Conclusion: the prevalence rate of gastrointestinal diseases diagnosed by Rome 鈪，

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