2015年江门市登革热疫点245名健康人群血清流行病学调查

发布时间：2018-06-30 06:31

本文选题：登革热 + 血清流行病学　；参考：《现代预防医学》2017年07期

【摘要】：目的了解登革热疫点健康人群感染状况,为预防及控制登革热提供依据。方法在江门市江海区礼乐街道2014年曾发生登革热疫情的4个疫点随机抽取245名身体健康、2周内无发热史且无登革热病史的本地居民,采集血清标本并用酶联免疫法检测血清中抗登革病毒IgG抗体,与非疫点健康人群的血清标本进行对比。在疫点开展问卷调查,调查登革热感染因素,并进行非条件Logistic回归分析。结果登革热疫点健康人群抗登革病毒IgG抗体阳性率24.49%(60/245),非疫点抗体阳性率3.09%(13/421),两者差异具有统计学意义(X~2=72.69,P0.001)。抗体阳性率随着年龄的上升而下降(趋势检验X~2=7.07,P0.05)。经过单因素和多因素非条件Logistic回归分析,影响登革热IgG抗体阳性率的因素有:蚊帐的使用,水生植物的种养和家中环境。结论登革热暴发疫点健康人群感染比例较高,需要针对高危因素预防和控制登革热的流行。
[Abstract]:Objective to investigate the infection status of healthy population in dengue fever epidemic area and to provide evidence for prevention and control of dengue fever. Methods 245 local residents who had no history of fever and had no history of dengue fever within 2 weeks were randomly selected from 4 epidemic sites where dengue fever had occurred in Lile Street of Jiangmen City in 2014. Serum samples were collected and detected by enzyme-linked immunosorbent assay (Elisa). A questionnaire survey was conducted to investigate the risk factors of dengue fever infection, and non-conditional logistic regression analysis was carried out. Results the positive rate of anti-dengue virus IgG antibody was 24.49% (60 / 245) and that of non-epidemic point antibody was 3.09% (13 / 421). The positive rate of antibody decreased with age (P 0.05). By univariate and multivariate unconditional logistic regression analysis, the factors influencing the positive rate of IgG antibody to dengue fever were: the use of mosquito nets, the breeding of aquatic plants and the home environment. Conclusion the prevalence of dengue fever is high in the healthy population, so it is necessary to prevent and control the prevalence of dengue fever according to the high risk factors.
【作者单位】：江门市疾病预防控制中心;
【基金】：江门市科技局科研项目(江科[2015]77号)
【分类号】：R512.8;R183

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