南京市人感染H7N9禽流感流行病学调查

发布时间：2018-08-23 12:01

【摘要】：目的了解人感染H7N9禽流感的流行病学特征,为制定防控措施提供依据。方法按照《人感染H7N9禽流感流行病学调查方案》进行流行病学调查,通过排列疾病时间、收集病例诊疗经过、确定密切接触者;通过现场勘调查揭示病例暴露情况,结合实验室检测结果综合诊断病例。结果确诊的11例病例中,有2例从事家禽宰杀,4例常去农贸市场。初期临床表现主要为流感样症状,抗生素治疗效果不明显,并迅速发展为重症肺炎。呼吸道分泌物样本人感染H7N9禽流感病毒核酸检测均为阳性。208名密切接触者均未发现人感染H7N9禽流感病毒感染。结论病例病情进展迅速,病情较重,病死率较高;缺少H7N9禽流感人传人的证据;加强对禽类检疫管理,可以消除和控制人感染H7N9禽流感疫情的发生。
[Abstract]:Objective to investigate the epidemiological characteristics of human infection with H7N9 avian influenza and to provide evidence for the prevention and control measures. Methods according to the "Epidemiological investigation Program for Human infection with H7N9 Avian Influenza", an epidemiological investigation was carried out. By arranging the time of the disease and collecting the course of diagnosis and treatment of the case, the close contacts were determined, and the exposure of the case was revealed through the on-the-spot investigation. Combined with laboratory test results comprehensive diagnosis of cases. Results of the 11 confirmed cases, 2 cases were engaged in poultry slaughter and 4 cases went to farmers' market. The initial clinical manifestations were mainly influenza-like symptoms and the effect of antibiotic therapy was not obvious and developed rapidly into severe pneumonia. Respiratory secretions from human infected with H7N9 avian influenza virus nucleic acid detection was positive. 208 close contacts did not find human infection with H7N9 avian influenza virus infection. Conclusion the disease progress is rapid, the disease is serious, the mortality is high, the evidence of human-to-human transmission of H7N9 avian influenza is lacking, and the poultry quarantine management can eliminate and control the occurrence of human infection with H7N9 avian influenza.
【作者单位】：南京市疾病预防控制中心;
【分类号】：R181.3

【共引文献】