2013-2016年潍坊市疑似预防接种异常反应监测分析

发布时间：2018-10-16 13:25

【摘要】：目的分析2013-2016年潍坊市疑似预防接种异常反应(adverse events following immunization,AEFI)的发生特征,评价AEFI监测系统的运转情况和预防接种的安全性。方法通过AEFI信息管理系统收集2013-2016年潍坊市AEFI个案数据,采用描述性流行病学方法对相关指标进行分析。结果 2013-2016年潍坊市共计报告AEFI病例6746例,其中一般反应6 706例,占99.41%;异常反应35例,占0.52%;偶合症5例,占0.07%。2岁共5 070例,占75.16;1岁儿童3 291例,占48.78%。发生数较多的依次为9月龄为514例,占15.82%;8月龄477例,占14.68%;10月龄410例,占12.62%;5月龄391例,占12.03%;6月龄336例,占10.34%。发生多在接种1d内5 762例,占85.41%。发生最多的临床症状为发热/红肿/硬结6 706例,占99.41%。发生数较多的疫苗依次为无细胞百白破疫苗1 888例,占27.99%,乙脑减毒活疫苗1 066例,占15.80%,麻风疫苗464例,占6.88%。结论潍坊市AEFI监测系统的完整性和敏感性逐年提高,需要进一步加强AEFI监测工作,规范预防接种操作,严格掌握接种禁忌证,减少AEFI发生。
[Abstract]:Objective to analyze the characteristics of suspected vaccination abnormal reaction (adverse events following immunization,AEFI) in Weifang from 2013 to 2016, and to evaluate the operation of AEFI monitoring system and the safety of vaccination. Methods the data of AEFI cases in Weifang from 2013 to 2016 were collected by AEFI information management system, and the related indexes were analyzed by descriptive epidemiological method. Results A total of 6746 cases of AEFI were reported in Weifang from 2013 to 2016, including 6 706 cases of general reaction (99.41%), 35 cases of abnormal reaction (0.52%), 5 cases of incidental disease (0.07.2 years old), 5 cases of 5 070 cases (0.07.2 years old), and 3 291 cases (48.78%) of 75.161-year-old children. There were 514 cases of 9 months old, 477 cases of 15.82 months old, 410 cases of 14.68 and 10 months old, 391 cases of 12.62g / 5 months old, 336 cases of 12.03 / 6 months old, and 10.34 cases. Most of them occurred in 5762 cases (85.41%) within 1 day of inoculation. The most common clinical symptoms were fever / redness / sclerosis in 6 706 cases (99.41%). The most common vaccines were acellular white tetanus vaccine (1 888 cases), encephalitis B attenuated live vaccine (1 066 cases, 15.80%) and leprosy vaccine (464 cases, 6.88%). Conclusion the integrity and sensitivity of the AEFI monitoring system in Weifang have been improved year by year. It is necessary to further strengthen the monitoring of AEFI, standardize the inoculation operation, strictly grasp the contraindications of inoculation, and reduce the incidence of AEFI.
【作者单位】：潍坊市疾病预防控制中心;
【分类号】：R186

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