血吸虫尾蚴电子杀灭技术研究

发布时间：2018-11-11 07:35

【摘要】： 血吸虫病严重危害人们身体健康,导致大量患者劳动力丧失;严重影响了经济发展,带来的不安定因素阻碍了社会的和谐与稳定。因此,血吸虫的防治具有重大意义。杀灭血吸虫尾蚴,切断血吸虫的感染途径,破坏其生命周期,是彻底根除血吸虫病的最有力方法。针对常用的化学药物杀灭法存在的易使尾蚴产生抗药性、水域宽广致使药效降低、污染环境、毒杀其它生物等弊端,本文提出了一种利用高压脉冲电场杀灭血吸虫尾蚴的新方法,探讨了这种电子杀灭方法的可行性,分别研究了采用锐形电极和平板电极的血吸虫尾蚴杀灭机理,分析了影响尾蚴杀灭效果的各种因素,介绍了实验阶段血吸虫尾蚴高压脉冲电场杀灭系统的构成,指出了系统研制和试验过程中需要充分考虑的安全性问题。本文共分为五章。第一章描述血吸虫的生长周期及分布、血吸虫对宿主的危害,说明杀灭血吸虫的重大意义,指出本文的研究背景和主要内容。第二章阐述现有的直接和间接血吸虫杀灭技术的基本原理、特点和适用场合,介绍血吸虫杀灭技术研究现状,指出血吸虫杀灭方法的发展趋势。第三章主要介绍尾蚴的超微结构,探讨采用血吸虫尾蚴高压脉冲电场杀灭技术的可行性,研究血吸虫尾蚴高压脉冲电场杀灭技术的机理,分析影响杀灭效果的电场参数、处理环境和生物特性因素。第四章介绍血吸虫尾蚴高压脉冲电场杀灭系统的功能和组成,探讨电极材料的选取、电极的吸附效应与改善方法。第五章介绍系统在防尾蚴感染、防电磁波、防静电和高压区域隔离方面的安全性设计。最后结论部分总结文章的创新和不足。血吸虫尾蚴高压脉冲电场杀灭方法能避免传统化学药物杀灭血吸虫尾蚴的不足,还具有水面杀菌、净化水域的环保效果,具有积极的社会意义和广阔的应用前景,为消灭血吸虫探究了一种新方法,可望为绿色血防开辟崭新途径。
[Abstract]:Schistosomiasis seriously endangers people's health and results in the loss of labor force of a large number of patients. It seriously affects the economic development and the unstable factors hinders the harmony and stability of the society. Therefore, the prevention and cure of Schistosoma japonicum is of great significance. Killing schistosomiasis cercariae, cutting off the way of schistosomiasis infection and destroying its life cycle are the most powerful ways to eradicate schistosomiasis. The common methods of killing cercariae are easy to make cercariae resistant to drug, the wide water area leads to the decrease of drug efficacy, the pollution of the environment, the poisoning of other organisms, and so on. In this paper, a new method of killing schistosomiasis cercariae by high voltage pulsed electric field is proposed. The feasibility of this method is discussed. The killing mechanism of Schistosoma cercariae with sharp electrode and plate electrode is studied respectively. The factors influencing the killing effect of cercariae were analyzed. The structure of the system for killing cercariae in the experiment stage was introduced, and the safety problems needed to be considered in the development and test of the system were pointed out. This paper is divided into five chapters. The first chapter describes the growth cycle and distribution of Schistosoma japonicum, the harm of Schistosoma japonicum to the host, explains the significance of killing schistosome, and points out the research background and main contents of this paper. The second chapter describes the basic principle, characteristics and application of the existing direct and indirect schistosomiasis killing techniques, introduces the present situation of schistosomiasis killing technology, and points out the development trend of schistosomiasis killing methods. Chapter 3 mainly introduces the ultrastructure of cercariae, discusses the feasibility of killing cercariae by high voltage pulse electric field, studies the mechanism of killing cercariae by high voltage pulse electric field, and analyzes the electric field parameters that affect the killing effect. Deal with environmental and biological characteristics. In chapter 4, the function and composition of the system for killing schistosomiasis cercariae by high voltage pulsed electric field are introduced. The selection of electrode material, the adsorption effect of electrode and the improvement method are discussed. Chapter 5 introduces the safety design of the system in preventing cercariae infection, electromagnetic wave, static electricity and high voltage area isolation. The last part of the conclusion summarizes the innovation and deficiency of the article. The method of killing schistosomiasis cercariae by high voltage pulse electric field can avoid the shortage of traditional chemical drugs killing schistosomiasis cercariae, and it also has the effect of water surface sterilization and purification of water area, which has positive social significance and broad application prospect. In order to eliminate schistosomiasis, a new method is explored, which is expected to open up a new way for green blood control.
【学位授予单位】：湖南大学
【学位级别】：硕士
【学位授予年份】：2006
【分类号】：R184

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