不同地区青年男性急性高原反应差异分析

发布时间：2018-11-25 20:59

【摘要】：目的调查不同地区青年男性进藏后急性高原反应(AMS)的发生情况,探讨不同地区人群高原环境适应能力的医学地理学差异。方法对从不同地区进入高原的青年男性AMS发生情况进行整群抽样调查,参照军用标准,采用AMS症状学评分法对其进行分度与评分。为区分不同地理环境差异,对人员生活所在地自然地理因素进行系统聚类分析,并用非参数检验进行验证。采用单因素方差分析研究不同地区青年男性AMS症状评分的差异。结果根据聚类分析结果将研究对象生活所在地分为5个地区,各组地理指标之间差异具有统计学意义(P0.01)。研究显示不同地区人群AMS的发生率存在显著差异(P0.05),其中地区2人员的AMS发生率显著高于地区3、4、5(P0.05)。地区2人员头痛发生率为82.8%,与地区3、4、5比较差异有统计学意义(P0.05),乏力和嗜睡症状发生率分别为72.4%、27.6%,与地区5比较差异有统计学意义(P0.05),恶心、呕吐症状发生率为37.9%,与地区3比较,差异有统计学意义(P0.05)。地区1和地区3人员眼花症状发生率与地区5比较差异具有统计学意义(P0.05)。结论不同地区人群AMS的发生存在明显医学地理差异,不同地区人群对高原的适应能力有所不同,来自低海拔地区人群的AMS症状较高海拔地区人群重。应根据人群地域差异采取有针对性的AMS防护措施。
[Abstract]:Objective to investigate the occurrence of acute high altitude reaction (AMS) in young men from different regions and to explore the difference of their medical geography in adapting to environment in different regions. Methods the incidence of AMS in young men from different areas to plateau was investigated by cluster sampling. According to the military standard, AMS symptom scoring method was used to grade and score it. In order to distinguish the difference of different geographical environment, the author makes a systematic cluster analysis of the natural geographical factors in the place where the personnel live, and verifies it by non-parametric test. Univariate analysis of variance (ANOVA) was used to study the difference of AMS symptom score among young men in different areas. Results according to the results of cluster analysis, the living places of the subjects were divided into 5 regions, and the differences among the geographical indexes were statistically significant (P0.01). The results showed that there was significant difference in the incidence of AMS among different population groups (P0.05), and the incidence of AMS in area 2 was significantly higher than that in area 3 (P0.05). The incidence of headache in area 2 was 82.8, and the difference was statistically significant (P0.05). The incidence of fatigue and somnolence were 72.4% and 27.662%, respectively. Compared with area 5, the incidence of nausea and vomiting was 37.9, and the difference was statistically significant compared with area 3 (P0.05). The incidence of eye symptom in area 1 and 3 was significantly different from that in area 5 (P0.05). Conclusion there are obvious medical geographical differences in the occurrence of AMS in different areas, and the adaptability of different populations to the plateau is different. The AMS symptoms of people from low altitude areas are heavier than those from high altitude areas. AMS protection measures should be taken according to the regional differences of population.
【作者单位】：第三军医大学高原军事医学系军事医学地理学教研室、高原医学教育部重点实验室、全军高原医学重点实验室;
【基金】：国家自然科学基金(41201090)~~
【分类号】：R188

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