针灸及穴位注射致非结核分枝杆菌感染的临床研究

发布时间：2019-01-04 13:20

【摘要】：目的探讨针灸及穴位注射致非结核分枝杆菌感染后的临床表现、治疗方法等,以期提高该病诊治水平。方法随机选取2011年2月-2013年1月由针灸及穴位注射致非结核分枝杆菌感染46例患者为研究对象,分析其在临床上的特征等;采用SPSS13.0软件进行分析。结果针灸及穴位注射致非结核分枝杆菌感染临床表现主要有肢体的肿痛和硬结,其他的有波动或破溃流脓、冷脓肿和肺结核样症状;治疗前后的评分差异有统计学意义(P0.05),其中27例患者治疗6个月内痰培养转阴,转阴率为58.7%,3例患者因为治疗4周后出现肝功能损害而被迫停药,其他的均完成治疗,随访18个月后,痰培养转阴41例,转阴率为89.13%;非结核分枝杆菌对异烟肼耐药率最高,为89.13%,对丙硫异烟胺的耐药率最低,为10.87%;耐1种药物36例耐药率为78.26%、耐2种13例耐药率为28.26%、耐≥3种4例耐药率为8.7%。结论早期综合措施治疗针灸及穴位注射致非结核分枝杆菌感染的临床效果较满意。
[Abstract]:Objective to investigate the clinical manifestations and treatment methods of nontuberculous mycobacterium infection caused by acupuncture and acupoint injection in order to improve the diagnosis and treatment of the disease. Methods from February 2011 to January 2013, 46 patients with nontuberculous mycobacterium infection caused by acupuncture and acupoint injection were randomly selected to analyze their clinical characteristics and so on. The results were analyzed by SPSS13.0 software. Results the clinical manifestations of non-tuberculous bacilli infection caused by acupuncture and acupoint injection mainly included swelling, pain and sclerosing of limbs, other symptoms such as fluctuating or ruptured pus, cold abscess and pulmonary tuberculosis. There was significant difference in the scores before and after treatment (P0.05). Among them, 27 cases had sputum culture turned negative within 6 months after treatment, and 3 cases had to stop treatment because of liver function damage after 4 weeks of treatment, and the rate of turning negative was 58.7%. All the others were treated. After 18 months follow-up, 41 cases of sputum culture turned negative, the negative rate was 89.13%. The resistance rate of non-tuberculosis Mycobacterium tuberculosis to isoniazid was the highest (89.13), and the resistance rate to propyl isoniacin was the lowest (10.87). The drug resistance rate was 78.26 in 36 patients with one drug resistance, 28.26 in 13 patients with 2 kinds of drug resistance, and 8.7 in 4 patients with resistance to more than 3 kinds of drugs. Conclusion the clinical effect of early comprehensive measures in the treatment of non-tuberculosis mycobacterium infection caused by acupuncture and acupoint injection is satisfactory.
【作者单位】：河南省南阳医学高等专科学校针灸骨伤系;
【基金】：河南省卫生厅专项基金资助项目(HW-2010B-1027)
【分类号】：R181.32

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