2008-2013年淮安市疑似预防接种异常反应监测分析

发布时间：2019-02-11 19:42

【摘要】：目的分析2008-2013年淮安市疑似预防接种异常反应(AEFI)的发生情况和特征,评价系统运行情况,为提高疫苗的安全性提供科学资料,有助于提高预防接种服务质量。方法通过AEFI信息管理系统收集2008-2013年报告的个案数据,采用描述流行病学研究方法进行分析。结果 2008-2013年淮安市AEFI监测系统共收到2 743例个案报告,报告发生率为29.99/10万,其中一般反应占93.22%,以发热/红肿/硬结为主,异常反应以过敏性皮疹为主,88.44%的AEFI都发生在24 h内,发生率较高的疫苗分别为无细胞百白破(85.53/10万)、麻疹/麻风(66.53/10万),麻腮风(23.57/10万)、乙脑(37.73/10万)。结论疫苗AEFI发生率都很低,免疫规划疫苗均是安全的;AEFI监测系统运转正常,监测的敏感性在逐步提高,将AEFI系统建成公众能报告的开放系统,有利于提高监测系统的敏感性。
[Abstract]:Objective to analyze the occurrence and characteristics of (AEFI) in Huaian city from 2008 to 2013, to evaluate the operation of the system, to provide scientific data for improving the safety of vaccine and to improve the quality of vaccination service. Methods the case data from 2008 to 2013 were collected by AEFI information management system and analyzed by descriptive epidemiology. Results from 2008 to 2013, a total of 2 743 cases were reported to the AEFI surveillance system in Huaian City, with a reported incidence of 29.99% / 100 000, of which 93.22% were general reactions, mainly fever / redness / sclerosis, and most abnormal reactions were allergic rash. 88.44% of AEFI occurred within 24 hours. The higher incidence rates were acellular white tetanus (85.53% / 100 000), measles / leprosy (66.53% / 100 000), parotid disease (23.57% / 100 000), and Japanese encephalitis (377.3% / 100 000). Conclusion the incidence of vaccine AEFI is very low and the immunization planning vaccine is safe, and the monitoring system of AEFI is running normally and the sensitivity of monitoring is increasing gradually. It is helpful to build AEFI system into an open system that can be reported by the public, which is helpful to improve the sensitivity of the monitoring system.
【作者单位】：淮安市疾病预防控制中心;
【分类号】：R186

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