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EV71疫苗接种意愿与接种行为差异分析

发布时间:2019-03-27 14:50
【摘要】:目的了解肠道病毒71型(EV71)疫苗接种行为及其与接种意愿差异的影响因素,以更好地发挥该疫苗的作用。方法在广东省广州市海珠区选取5个街道,于2016年6月在各街道接种门诊共选取1 483名6~35月龄儿童家长进行基线调查,其中1 113名于EV71疫苗投入使用约4个月后完成了随访调查,分析疫苗接种及其与接种意愿差异的影响因素。结果基线调查、随访调查的愿意接种率分别为81.39%、83.47%;1 113名随访调查者EV71疫苗接种率为67.30%,与接种意愿差异有统计学意义(χ~2=78.433,P=0.000)。家长认为疫苗安全或不清楚是否安全、认为疫苗可以≥70%或不确定多大概率预防手足口病以及听从接种医生的安排或建议是家长让儿童接种EV71疫苗的有利因素(P0.05);而儿童有手足口病史、较清楚EV71病毒与手足口病关系的家长则倾向于不让儿童接种EV71疫苗(P0.05)。对愿意接种者而言,认为疫苗安全或不清楚是否安全(OR_(很安全vs不安全)=5.264,OR_(一般vs不安全)=3.757,OR_(不清楚vs不安全)=1.582)是促使其将意愿转变为实际接种的因素,而认为疫苗价格较贵(OR_(贵vs便宜)=0.543)、较清楚EV71病毒与手足口病关系(OR_(清楚vs不清楚)=0.544,OR_(部分清楚vs不清楚)=0.731)则是阻碍其将意愿付诸行动的因素;对不愿接种者而言,听从接种医生的安排或建议(OR_(很大程度vs很小程度)=3.074,OR_(一般程度vs很小程度)=1.836)以及受朋友等其他人的影响较大(OR_(很大程度vs很小程度)=2.445)是促使其意愿转变并最终接种疫苗的因素,而清楚EV71病毒与手足口病关系(OR_(清楚vs不清楚)=0.416)则是使其坚持意愿不接种疫苗的因素。结论家长对EV71疫苗效果、安全性及EV71病毒与手足口病关系的认识以及接种医生的安排或建议是影响EV71疫苗接种的重要因素。
[Abstract]:Aim to understand the vaccination behavior of enterovirus 71 (EV71) vaccine and the influencing factors of the difference between enterovirus 71 vaccine and vaccination intention, so as to give full play to the effect of the vaccine. Methods five streets were selected in Haizhu District of Guangzhou City, Guangdong Province, and a total of 1 483 parents of 6-35-month-old children were selected from different street vaccination clinics in June 2016 for baseline survey. 1 113 of them were followed up about 4 months after the EV71 vaccine was put into use, and the influencing factors of vaccine vaccination and the difference between vaccination intention and vaccination intention were analyzed. Results in the baseline survey, the coverage rate of EV71 vaccine was 81.39%, 83.47% and 67.30% in the follow-up survey, respectively. There was a significant difference between the two groups (蠂 ~ 2, 78.43, P < 0.000). Parents think the vaccine is safe or not, believe that the vaccine can be 鈮,

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