农村人群空腹血糖水平与腰臀比及体质指数关系的研究

发布时间：2019-04-19 22:11

【摘要】：目的了解农村人群空腹血糖(fasting blood glucose,FBG)水平的分布及其与体质指数(body mass index,BMI)、腰臀比(waist-hip ratio,WHR)的关系。方法于2011年对安庆周边(东至县)农村地区人群进行横断面调查,收集相关资料,用多元Logistic回归分析WHR、BMI与糖尿病(diabetes mellitus,DM)之间的关系。结果共2 890例研究对象纳入分析,平均FBG为(5.81±1.53)mmol/L,DM粗患病率为9.9%,年龄标化患病率为3.2%;随着BMI的增加,FBG水平和DM患病率也呈增加趋势;BMI、WHR达肥胖标准(全身性肥胖或腹型肥胖)人群的FBG水平及DM患病率均比各自正常人群高。将BMI和WHR同时纳入模型,并在调整了年龄、性别、胆固醇、三酰甘油、舒张压、收缩压后,多元Logistic回归分析结果显示,WHR与DM患病相关联(OR=5.76,95%CI:2.67~12.43),而BMI与DM患病的关联性无统计学意义。结论腹型肥胖与DM患病有关,提示腹型肥胖者易发生DM。
[Abstract]:Objective to investigate the distribution of fasting blood glucose (fasting blood glucose,FBG) in rural population and its relationship with body mass index (body mass index,BMI) and waist hip ratio (waist-hip ratio,WHR). Methods A cross-sectional survey was conducted in rural areas around Anqing (Dongzhi County) in 2011. The data were collected and the relationship between WHR,BMI and diabetes mellitus (diabetes mellitus,DM) was analyzed by multiple Logistic regression. Results A total of 2 890 subjects were included in the study, the average FBG was (5.81 卤1.53) mmol/L,DM crude prevalence rate was 9.9%, age-standardized prevalence rate was 3.2%, and with the increase of BMI, FBG level and DM prevalence rate also showed an increasing trend. The level of FBG and the prevalence of DM in the subjects with BMI,WHR reaching the standard of obesity (systemic obesity or abdominal obesity) were higher than those in the normal population. After adjusting for age, sex, cholesterol, triacylglycerol, diastolic blood pressure and systolic blood pressure, multiple Logistic regression analysis showed that WHR was associated with DM disease (OR=5.76,95%CI:2.67~12.43), both BMI and WHR were incorporated into the model, and adjusted for age, sex, cholesterol, triacylglycerol, diastolic blood pressure and systolic blood pressure. There was no significant correlation between BMI and DM. Conclusion abdominal obesity is associated with DM, suggesting that abdominal obesity is prone to DM..
【作者单位】：安徽医科大学生物医学研究所;南方医科大学南方医院肾内科;连云港市现代心血管病防治研究中心;深圳大学生物医药研究所;
【基金】：国家自然科学基金(81202280) 广东省自然科学基金博士启动项目(S201204006973)
【分类号】：R181.2;R587.1

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