2009-2015年西北地区5岁以下儿童发热伴出疹症候群病原及流行病学特征分析

发布时间：2019-06-10 06:39

【摘要】：目的通过对西北四省区发热伴出疹症候群的监测,了解5岁以下儿童发热伴出疹症候群的病原构成及流行特征,为疾病监测及预防控制提供参考。方法采用描述性流行病学方法分析5岁以下儿童发热伴出疹症候群的病原及流行病学特征,数据为国家传染病监测技术平台信息管理系统2009-2015年甘肃、青海、内蒙古和新疆四省区发热伴出疹症候群哨点医院的监测数据。结果西北四省区5岁以下儿童发热伴出疹症候群病原构成以病毒为主,依次是肠道病毒、麻疹病毒、水痘病毒和风疹病毒等;各年龄段病原构成显示0~岁组病原构成主要是麻疹病毒,1~5岁组主要是肠道病毒;肠道病毒分型结果显示,肠道病毒71型(human enterovirus 71,EV71)占肠道病毒阳性病例数的47.18%,柯萨奇A16型(coxsackie A16,CA16)占45.59%;季节特征显示,肠道病毒阳性病例分布主要集中在每年的5~7月,麻疹病毒阳性病例分布主要集中在每年的3~5月。结论西北地区5岁以下儿童发热伴出疹症候群病原构成以病毒为主且具有明显的季节特征,应加强麻疹、手足口等疾病的监测和预防控制工作。
[Abstract]:Objective to investigate the pathogen composition and epidemic characteristics of fever with rash syndrome in children under 5 years old by monitoring fever with rash syndrome in four provinces of Northwest China, so as to provide reference for disease surveillance, prevention and control. Methods descriptive epidemiological method was used to analyze the pathogen and epidemiological characteristics of fever with rash in children under 5 years old. The data were as follows: the information management system of the National Infectious Disease Surveillance Technology platform 2009-2015 in Gansu and Qinghai. Monitoring data of fever with rash syndrome sentinel hospitals in Inner Mongolia and Xinjiang provinces. Results the main pathogens of fever with rash in children under 5 years old in the four provinces of Northwest China were enterovirus, measles virus, varicella virus and rubella virus, among which enterovirus, measles virus, varicella virus and rubella virus were the main pathogens. The pathogen composition of each age group showed that the pathogen composition of 0 ~ year old group was mainly measles virus, and that of 1 ~ 5 years old group was mainly enterovirus. The results of enterovirus typing showed that enterovirus 71 (human enterovirus 71 accounted for 47.18% of enterovirus positive cases, coxsackie A16 (coxsackie A16, CA16) accounted for 45.59%. The seasonal characteristics showed that the distribution of enterovirus positive cases was mainly from May to July of each year, and the distribution of measles virus positive cases was mainly from March to May of each year. Conclusion the main pathogen of fever with rash syndrome in children under 5 years old in Northwest China is virus and has obvious seasonal characteristics. The surveillance, prevention and control of measles, hand, foot and mouth diseases should be strengthened.
【作者单位】：兰州大学公共卫生学院流行病与卫生统计学研究所;甘肃省疾病预防控制中心急性传染病防制科;
【基金】：“十二五”国家科技重大专项(2012ZX10004-208) 中央高校基本科研业务费项目(lzujbky-2015-265)
【分类号】：R181.3;R725.1

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