不同麻醉方法对老年患者下肢手术时对血小板及血流动力学的影响

发布时间：2017-12-30 19:15

本文关键词：不同麻醉方法对老年患者下肢手术时对血小板及血流动力学的影响　出处：《血栓与止血学》2016年01期 　论文类型：期刊论文

【摘要】：目的研究不同麻醉方法对老年人下肢手术患者血小板活化指标及血流动力学的影响。方法以我院2012年6月~2014年6月择期行下肢手术的80例老年患者为研究对象,随机双盲法将其分为两组,各40例。对照组给予全身麻醉,观察组则行全身麻醉联合硬膜外麻醉,比较两组不同时间点血流动力学及血小板活化等指标。结果两组不同时间点(麻醉前、麻醉后10 min、麻醉后30 min、术毕)SBP、DBP、HR、Sp O2无显著变化(P0.05)。两组术后3d血小板聚集率[(49.52±9.50)VS(54.61±10.12)]%、Fbg[(3.89±1.13)VS(5.33±2.12)]g/L、红细胞聚集指数[(1.92±0.17)VS(2.10±0.14)]、血浆黏度[(1.42±0.1)VS(1.50±0.12)]m Pa/s、血浆还原粘度[(9.60±0.50)VS(10.46±0.53]m Pa/s比较差异有统计学意义(P0.05)。结论全身麻醉、全麻联合硬膜外麻醉均能较好的维持患者血流动力学稳定,但后者更能减少对血小板活化指标的影响。
[Abstract]:Objective to study the effects of different anesthetic methods on platelet activation and hemodynamics in elderly patients undergoing lower extremity surgery. Methods 80 elderly patients undergoing lower extremity surgery from June 2012 to June 2014 were selected in our hospital. Patients were studied. They were randomly divided into two groups, 40 cases each. The control group was given general anesthesia, while the observation group was given general anesthesia combined with epidural anesthesia. Results at different time points (before anesthesia, 10 min after anesthesia, 30 min after anesthesia), the blood flow and platelet activation were compared between the two groups. There was no significant change of Sp O 2 in HRG and P 0.05%. The platelet aggregation rate was 3 days after operation in both groups. [FBG (49.52 卤9.50 VSN 54.61 卤10.12). [3.89 卤1.13 VSN 5.33 卤2.12] g / L, erythrocyte aggregation index. [Plasma viscosity. [Plasma reductive viscosity. [There was a significant difference in Pa/s between 9.60 卤0.50 and 10.46 卤0.53 m Pa/s. General anesthesia combined with epidural anesthesia can maintain hemodynamic stability, but the latter can reduce the effect on platelet activation.
【作者单位】：汉川市人民医院日间手术室;
【分类号】：R614
【正文快照】： 彭甫圣(PENG Fu-sheng),付珍红(FU Zhen-hong)(汉川市人民医院日间手术室,汉川,431600;Department ofAnesthesia,Hanchuan People’s Hospital,Hanchuan,431600,China)近年来,老年人下肢手术病例在我国人口老龄化现象加剧形势下逐年增多,由于老年患者生理机能退变、合并糖尿病

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