丙泊酚和七氟烷在患儿全身麻醉中对血流动力学、术后苏醒质量的影响对比研究

发布时间：2017-12-31 14:24

本文关键词：丙泊酚和七氟烷在患儿全身麻醉中对血流动力学、术后苏醒质量的影响对比研究　出处：《北方药学》2016年10期 　论文类型：期刊论文

【摘要】：目的:评价丙泊酚与七氟烷在患儿全身麻醉中的应用效果。方法:选择我院择期手术的180例腹股沟斜疝患儿,随机分为丙泊酚麻醉组和七氟烷麻醉组各90例。连续监测患儿收缩压(SBP)、心率(HR)、心电图(ECG)、舒张压(DBP)、麻醉深度(BIS)、血氧饱和度(Sp O2)、PETCO2。记录患儿麻醉诱导后(T1)、诱导前(T0)、气管插管即刻(T2)、插管后3min(T3)、手术完成时(T4)、睁眼时(T5)、完全清醒时(T6)的SBP、HR、DBP、BIS。结果:两组患儿组内各指标相比,麻醉诱导后收缩压和舒张压与诱导前比较明显下降(P0.05),七氟烷组患儿手术完成时拔管时间和术后苏醒时间与丙泊酚组相比,显著缩短(P0.05)。结论:丙泊酚与七氟烷麻醉均能有效降压,稳定心率,维持相当的麻醉深度,但是七氟烷苏醒质量更好。
[Abstract]:Objective: to evaluate the efficacy of propofol and sevoflurane in general anesthesia in children. Patients were randomly divided into propofol anesthesia group (n = 90) and sevoflurane anesthesia group (n = 90). The anesthetic depth was BISN, the blood oxygen saturation was determined by SPO _ 2 and PETCO _ 2. After anesthesia induction, T _ (1), T _ (0) and T _ (2) were recorded before induction and tracheal intubation (t _ (2)). Three minutes after intubation, the SBPHR-DBP-BISs were treated with T4, T5 and T6. Results: the indexes in the two groups were compared. The systolic and diastolic blood pressure decreased significantly after anesthesia induction compared with that before induction. The extubation time and postoperative recovery time in sevoflurane group were compared with those in propofol group. Conclusion: both propofol and sevoflurane anesthesia can effectively reduce blood pressure, stabilize heart rate and maintain considerable anesthetic depth, but the recovery quality of sevoflurane is better.
【作者单位】：惠州市第三人民医院;
【分类号】：R726.1
【正文快照】： 患儿身体重要脏器功能的减退,患儿的全身麻醉是临床工作中常遇到的复杂问题,苏醒延迟,麻醉过深,麻醉过浅,增加术后并发症的发生率,术中血流动力学波动较大,加上应激状态下的适应能力和代偿能力较差[1],选择应激反应小,对患儿正常生理功能干扰小,术后恢复快的麻醉药物尤为重要

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